1-Amino-2-phenylethane derived sulfonamides - Abbasi, Muhammad Athar;Siddiqui, Sabahat Zahra
29,99 €
inkl. MwSt.
Versandkostenfrei*
Versandfertig in 1-2 Wochen
payback
15 °P sammeln
  • Broschiertes Buch

The presented study encompasses the synthesis of a series of sulfonamides derivatives of 1-amino-2-phenylethane in excellent yield by reaction with various aryl sulfonyl chlorides, in the presence of aqueous sodium carbonate solution under dynamic pH control. These projected structures of the synthesized derivatives were characterized by IR, 1H-NMR and EIMS spectral techniques. Moreover, the screening of derivatives against acetyl cholinesterase (AChE), butyryl cholinesterase (BChE) and lipoxygenase (LOX) enzymes rendered these molecules as potent inhibitors of cholinesterase enzymes, relative…mehr

Andere Kunden interessierten sich auch für
Produktbeschreibung
The presented study encompasses the synthesis of a series of sulfonamides derivatives of 1-amino-2-phenylethane in excellent yield by reaction with various aryl sulfonyl chlorides, in the presence of aqueous sodium carbonate solution under dynamic pH control. These projected structures of the synthesized derivatives were characterized by IR, 1H-NMR and EIMS spectral techniques. Moreover, the screening of derivatives against acetyl cholinesterase (AChE), butyryl cholinesterase (BChE) and lipoxygenase (LOX) enzymes rendered these molecules as potent inhibitors of cholinesterase enzymes, relative to Baicalein and Eserine, which were used as reference standard.
Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Autorenporträt
Muhammad Athar Abbasi (Assoc. Prof., GCU, Lahore) is HEC approved supervisor. He is a recipient of Research Productivity Award from 2008-14 from PCST, Pakistan. He has authored 141 research papers.Sabahat Zahra Siddiqui (Lecturer, GCU, Lahore) has authored 40 research publications. She worked as a research scholar at University of Pennsylvania.