Anoop Kumar Pathak, Viney Chawla, Shailendra K. Saraf

1,3-Pyrimidine Derivatives

Synthesis and Antimicrobial Activity

• Broschiertes Buch

Produktbeschreibung

There has been growing menace of antibiotic resistance in recent past owing to a number of reasons such as self medication and non-compliance on parts of patients with regard to complete dosage regimen. Medicinal chemists are hard pressed to bring about new molecules to cater to this need. 1,3-pyrimidine derivatives have been explored by a number of scientists worldwide and such these derivatives have emerged potential lead molecules for development of newer antimicrobial moieties. The present work reports the syntheses and evaluation of some 2-(6 -fluorobenzothiazol-2 -ylamino)-4,6-(disubstituted thiouriedo) -1,3-pyrimidine derivatives. Some of the synthesized derivatives showed excellent activity against Gram +ve bacteria Staphyllococcus aureus, Bacillus subtilis, and Gram -ve bacteria Escherichia coli and Pseudomonas aeruginosa. The contents of this book must make an excellent read for those interested in antibiotic research and allied interests.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Aufl.
• Seitenzahl: 116
• Englisch
• Abmessung: 220mm
• ISBN-13: 9783848488353
• ISBN-10: 3848488353
• Artikelnr.: 35550070

Autorenporträt

Assistant Professor since four years at N.N.M. College of Pharmacy, Nawabganj, Gonda, India.Studied M. Pharm. at Faculty of Pharmacy, BBDNIIT, Lucknow, India. Has active interest in medicinal agents acting as antimicrobials. Has published research paper on 1, 3-pyrimidine derivatives as antimicrobial agents.