This book is designed for undergraduate, postgraduate and researchers of organic chemistry to provide them ready reference regarding the synthesis as well as biological evaluation of 2-cyclic amine substituted benzoxazoles. This book contains systematic detailed information regarding the application of zinc dust as a reusable reagent in synthesis of 2-cyclic amine benzoxazoles under microwave irradiation conditions. It also includes anticancer, antibacterial, antifungal and anti-inflammatory activities studies of 2-cyclic amine benzoxazoles. I hope this book will be helpful to the students studying the chemistry of these heterocycles as well researcher interested in synthesis and medicinal applications of them.