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This book is designed to present the essentials of the nucleus 'imidazole' in the field of pharmacy.Perhaps this book may serve as a text and reference guide to under graduate as well as post graduate students for research on imidazole nucleus.It contains microwave assisted organic synthesis,spectral studies which comprises of Ultraviolet,Infrared,Mass,NMR spectroscopy, antimicrobial screening and invitro membrane stabilizing and antioxidant activity of 2- substituted 4,5-diphenyl imidazole derivatives. The topics and the extent to which they are dealt with have necessarily been arbitrary and are in part a reflection of the author's personal interests.