Andere Kunden interessierten sich auch für
![Total Synthesis of Indole Alkaloids]( "Total Synthesis of Indole Alkaloids")
Total Synthesis of Indole Alkaloids74,99 €![Total Synthesis of Indole Alkaloids]( "Total Synthesis of Indole Alkaloids")
Total Synthesis of Indole Alkaloids74,99 €![Novel Synthetic Chemistry of Ureas and Amides]( "Novel Synthetic Chemistry of Ureas and Amides")
Novel Synthetic Chemistry of Ureas and Amides74,99 €![Concise Organic Chemistry]( "Concise Organic Chemistry")
Concise Organic Chemistry51,99 €![Neurotrophic Natural Products]( "Neurotrophic Natural Products")
Neurotrophic Natural Products132,99 €![Progress in the Chemistry of Organic Natural Products 118]( "Progress in the Chemistry of Organic Natural Products 118")
Progress in the Chemistry of Organic Natural Products 118125,99 €![The Chemistry of Diamondoids]( "The Chemistry of Diamondoids")
The Chemistry of Diamondoids113,99 €
Christian Knittl-Frank reports on the development of a novel synthetic route to the naturally occurring polyhydroxylated oleanane, hederagonic acid. Polyhydroxylated oleananes are a vast family of naturally occurring triterpenoids with versatile biological activities. A low commercial availability combined with high prices make these molecules interesting targets in natural product synthesis. The developed synthetic approach starts from oleanolic acid, a cheap material that is commercially available in bulk quantities. It features several multi-step one-pot reactions, allowing a minimization of the number of steps and reducing the preparative effort. Importantly, catalytic C-H functionalization was achieved at unusually low temperatures. Hederagonic acid was thus prepared in as little as four steps, resulting in the shortest semisynthesis of this oleanane to date.
The Author
Christian Knittl-Frank is currently pursuing his PhD studies, focusing on natural product synthesis and synthetic methodology, at the Department of Organic Chemistry, University of Vienna, Austria. He is part of the MolTag doctoral program that aims to development new molecular drugs targeting ion channels.
The Author
Christian Knittl-Frank is currently pursuing his PhD studies, focusing on natural product synthesis and synthetic methodology, at the Department of Organic Chemistry, University of Vienna, Austria. He is part of the MolTag doctoral program that aims to development new molecular drugs targeting ion channels.