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Indigofera lupatana Baker F. (locally known as Mugiti) has been used to treat cough, diarrhea, pleurisy and gonorrhea. These and other infectious diseases are a cause of morbidity and mortality in humans and animals. Their effects are further aggravated by drug resistance. There is also increased emergence and re-emergence of infections from previously harmless micro-organisms, as part of nosocomial and opportunistic infections. This calls for search of new drugs that will mitigate these problems. Indigenous plants are promising as a cheap alternative source of new therapeutic agents. Although…mehr

Produktbeschreibung
Indigofera lupatana Baker F. (locally known as Mugiti) has been used to treat cough, diarrhea, pleurisy and gonorrhea. These and other infectious diseases are a cause of morbidity and mortality in humans and animals. Their effects are further aggravated by drug resistance. There is also increased emergence and re-emergence of infections from previously harmless micro-organisms, as part of nosocomial and opportunistic infections. This calls for search of new drugs that will mitigate these problems. Indigenous plants are promising as a cheap alternative source of new therapeutic agents. Although the use of phytomedicine has been in practice for long, little has been done to evaluate their effectiveness, safety, target organisms and also their chemical characterization. Therefore, the aim of this study was to investigate the antimicrobial activity, toxicity and phytochemical screening of root extracts of Indigofera lupatana Baker F. Powdered sample of I. lupatana Baker F. roots weresequentially extracted using hexane, ethyl acetate, dichloromethane and methanol solvents. The resultant fractions were subjected to anti-bacterial, phytochemical tests and brine shrimp toxicity bioassay.
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Autorenporträt
Mr Sospeter Ngoci Njeru is a graduate of Egerton University; BSc Biomedical Science and Technology, MSc Biochemistry and PhD student in Biochemistry.He is Currently a Lecturer in Kisii University College, Faculty of Health Sciences, Department of Medicine; a specialist in Ethnopharmacology, Drug discovery, Microbiology, Toxicology and Biochemistry