A Handbook of Bioanalysis and Drug Metabolism

Herausgeber: Evans, Gary

• Gebundenes Buch

Produktbeschreibung

This stimulating new handbook examines the techniques, methodology, and theory of bioanalysis and drug metabolism from the perspective of scientists with extensive professional experience in drug discovery and development. It covers topics such as high performance liquid chromatography, protein binding, pharmacokinetics and drug-drug interactions. A Handbook of Bioanalysis and Drug Metabolism is an invaluable guide for senior undergraduates and postgraduates studying drug metabolism in courses such as pharmaceutical science, pharmacology, chemistry, physiology and toxicology - especially those considering industrial placements or a career in the biotechnology industry.

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Produktdetails

• Verlag: Taylor & Francis Ltd (Sales)
• Seitenzahl: 416
• Erscheinungstermin: 29. März 2004
• Englisch
• Abmessung: 259mm x 176mm x 27mm
• Gewicht: 871g
• ISBN-13: 9780415275194
• ISBN-10: 0415275199
• Artikelnr.: 22064933

Autorenporträt

Gary Evans

Inhaltsangabe

The Role of Drug Metabolism and Pharmacokinetics in Drug Discovery: Past,
Present and Future. The Importance of the Physiochemical Properties of
Drugs to Drug Metabolism. Sample Preparation. High Performance Liquid
Chromatography in Pharmaceutical Bioanalysis. Quantitative Mass
Spectronomy. Immunoassay in Bioanalysis. Phase I Metabolism. Phase II
Enzymes. In vitro Techniques for Investigating Metabolism. Drug-Drug
Interactions: an in vitro Approach. Clinical Impact of Drug Interactions.
Preclinical Pharmacokinetics. Pharmacokinetic / Pharmacodynamic Modeling in
Preclinical Drug Discovery. Toxicokinetics. Protein Binding in Plasma: A
Case History of a Highly Protein Bound Drug. Metabolite Identification by
Spectroscopy. Whole Body Autoradiography. Radiolabeled Studies in Man.
Molecular Biology.