Mesoporous silica refers to a unique class of materials characterized by their well-ordered and interconnected network of nanoscale pores. These materials are primarily composed of silicon dioxide (SiO2), commonly known as silica, and exhibit a highly porous structure with pore sizes typically ranging from 2 to 50 nanometers. Overall, mesoporous silica combines a high surface area, controlled pore structure, and tunable surface properties, making it a versatile material with significant potential in diverse scientific and technological areas. In this review methods of synthesis, various uses and applications of mesoporous silica nanoparticles, limitations regarding them and future scope of studies are discussed.