Omadacycline, an antibiotic of the aminomethyl cycline class from the tetracycline family, was very recently discovered and is being used to treat ABSSSI.Omadacycline has demonstrated its effectiveness in the OASIS 1 and OASIS 2 trials with few side effects. In-depth information about the efficacy and safety of omadacycline in treating cellulitis is provided in this review, along with a summary of the highlights of the entire pharmacological profile.