Elemental medicine " Medical inorganic - chemistry " has grabbed the attention of researches in the field of inorganic chemistry [1-5] who are interested in coordination field between metal ions and antibiotics which a relatively short history beginning in the 1970' with the discovery and clinical development of anticancer drug cis-Platine [6]. In recent decades, rising infectious disease has been challenged with the increasing number of many -drug resistant pathogens. Thus, there is still a need to discover new compounds with enhanced biological activities to combat drug .