The plant source for the green synthesis of metal nanoparticles based on their particles stability and crystalline in nature, spherical in shape, smallest size with higher proportion of metal elemental composition and capability of acting as reducing, capping and stabilizing agent of metal nanoparticles. It includes the references and survey of various research paper, books, articles, thesis, etc., which have been studied to know the various techniques for the green synthesis and characterization of metal Nanoparticles and therapeutic applications of metal nanoparticles for antimicrobial and in vitro anticancer activity.