Clear cell lesions can be confront in a variety of states in maxillofacial region and constitute a heterogeneous group of lesions which may be either odontogenic, salivary gland or metastatic in origin however they are attributable to various factors including artifactual changes, improper cellular preservation, accumulation of glycogen, mucopolysaccharides or phagocytized foreign body material in the cytoplasm of tumor cells. This book gives a complete discussion on the classification system and clinical behavior of all the clear cell lesions encountered in maxillofacial region.