Accurate Results in the Clinical Laboratory

A Guide to Error Detection and Correction
Herausgeber: Dasgupta, Amitava; Sepulveda, Jorge L

• Gebundenes Buch

Produktbeschreibung

Erroneous hospital and pathology laboratory results can be confusing and problematic, especially in acute care situations when results may have life or death implications. While some factors creating interference, such as hemolysis or lipemia, can be identified in the laboratory, detecting many others is commonly dependent on clinical details unavailable to the laboratory scientists or pathologists. Therefore, clinicians and other health care providers must become proficient in identifying such erroneous reports and working with pathologists and laboratory scientists so that they can understand the source of such interferences, take the next steps to correct the results, and then decide what course of action must be followed for proper patient management. Interferences in laboratory reports due to drugs and herbal supplements are well documented in the clinical toxicology literature, but there is no one book on the market that covers the entire field of clinical laboratory interferences and erroneous laboratory results. this practical, easy-to-use guide will address interference issues in all laboratory tests, including patient epigenetics, process of specimen collection, enzymes, biomarkers, etc., so that clinicians and laboratory scientists can rely on one reference that speaks to both their needs of accurate specimen analysis and optimal patient care.

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Produktdetails

• Verlag: Elsevier Science
• Seitenzahl: 382
• Erscheinungstermin: 13. Februar 2013
• Englisch
• Abmessung: 284mm x 220mm x 25mm
• Gewicht: 1254g
• ISBN-13: 9780124157835
• ISBN-10: 0124157831
• Artikelnr.: 35330790

Inhaltsangabe

Chapter 1. Variation, Errors, and Quality in the Clinical Laboratory
Chapter 2. Effect of Age, Gender, Diet, Exercise and Ethnicity on
Laboratory Test Results
Chapter 3. Effect of patient preparation, specimen collection,
anticoagulants and preservatives on laboratory tests
Chapter 4. Sample processing and specimen misidentification issues
Chapter 5. Hemolysis, lipemia and high bilirubin: effect on laboratory
tests
Chapter 6. Immunoassay design and mechanism of interferences
Chapter 7. Effect of herbal remedies on clinical laboratory tests
Chapter 8. Challenges in routine clinical chemistry: analysis of small
molecules
Chapter 9. Challenges in routine clinical chemistry: proteins and enzymes
Chapter 10. Sources of inaccuracy in biochemical genetics analysis
Chapter 11. Challenges in endocrinology testing
Chapter 12. Pitfalls in tumor marker testing
Chapter 13. Issues of interferences in therapeutic drug monitoring
Chapter 14. Limitations of drugs of abuse testing
Chapter 15. Challenges in confirmation testing for drugs of abuse
Chapter 16. Alcohol determination using automated analyzers: limitations
and pitfalls
Chapter 17. Pre-analytical issues and interferences in transfusion medicine
tests
Chapter 18. Critical issues in immunology and serology testing
Chapter 19. Sources of errors in hematology and coagulation testing
Chapter 20. Challenges in Clinical Microbiology Testing
Chapter 21. Sources of errors in molecular testing
Chapter 22. Problems in Pharmacogenomics Testing