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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Acetic anhydride, or ethanoic anhydride, is the chemical compound with the formula (CH3CO)2O. Commonly abbreviated Ac2O, it is the simplest isolatable acid anhydride and is a widely used reagent in organic synthesis. (Formic anhydride spontaneously decomposes, especially once removed from solution.) It is a colorless liquid that smells strongly of acetic acid, formed by its reaction with the moisture in the air.