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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Activation syndrome is a form of sometimes suicidal or homicidal stimulation or agitation that can occur in response to some psychoactive drugs. A study of paroxetine found that 21 out of 93 (23 percent) of youth taking Paxil reported manic-like symptoms which included hostility, emotional lability and nervousness. Pfizer has denied that sertraline can cause such effects. Approximately 25 to 40 perecent of patients who take tricyclic antidepressants experience activation syndrome upon initial titration. Homicidal is a 1961 thriller film produced and directed by the self-proclaimed "King of Showmanship", William Castle. Written by Robb White, the film stars Glenn Corbett, Patricia Breslin, Eugenie Leontovich, Alan Bunce, Richard Rust, and Joan Marshall (billed as Jean Arless). It was released with a "fright break" that allowed patrons to receive a refund if they were too scared to stay for the climax of the film.