Acute Brain Impairment

Scientific Discoveries and Translational Research
Herausgeber: Peplow, Philip V; Martinez, Bridget; Gennarelli, Thomas A; Dambinova, Svetlana A

• Gebundenes Buch

Produktbeschreibung

A rise in the number of young and old patients suffering from a stroke or traumatic brain injury has led to the need for better drug development and treatment, as well as diagnosis and prevention of ischemic stroke and traumatic brain injury. This book provides a comprehensive overview of scientific advancements in these areas. Chapters provide the latest knowledge in neuroscience, biotechnology, and personalized medicine applicable to acute brain injuries. Development of neuroprotective drugs is treated in detail. Chemical biomarkers for detection, imaging and preventative strategies are covered to provide medicinal chemists with a broad view of translational aspects of the field. This book will be useful to postgraduate students and researchers in medicinal chemistry and pharmacology as well as specialists in the acute brain injury field.

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Produktdetails

• Verlag: RSC Publishing
• Seitenzahl: 368
• Erscheinungstermin: 22. November 2017
• Englisch
• Abmessung: 234mm x 160mm x 25mm
• Gewicht: 680g
• ISBN-13: 9781782629504
• ISBN-10: 1782629505
• Artikelnr.: 48924162

Inhaltsangabe

Transient Ischemic Attack, Traumatic Brain Injury, and Ischemic Stroke:
Risk Factors and Treatments; Inflammatory Changes in Cerebral Ischemic
Injury: Cellular and Molecular Involvement; Biomarkers of Acute Brain
Injury and Surrogate Endpoints in Traumatic Brain Injury and Stroke
Translational Studies; Difficulties of Translating Outcomes from Animal
Studies to Clinical Trials; Neuroprotective Therapies for Ischemic Stroke;
The Molecular Neuroprotective Strategies in Cerebral Ischemia: An Insight
into Emerging Treatments for Oxidative Stress; Identification of MicroRNAs
as Targets for Treatment of Ischemic Stroke; Combined Drug-Diagnostic Test
Co-development for Predicting and Preventing Brain Impairments; Advances in
Diagnostics and Treatment of Neurotoxicity after Sports-related Injuries;
Functional Predictors for Prognosis and Recovery after Mild Traumatic Brain
Injury; Predictors for Prognosis and Recovery from Unconsciousness Due to
Brain Trauma; Neurotoxicity in Spinal Cord Impairments; Advanced Approaches
in Stem Cell Therapy for Stroke and Traumatic Brain Injury; Testing and
Mechanisms of Neuroprotective Agents for Cerebral Ischemic Injury in
Clinical Trials, 2010-2016; Difficulties in Clinical Trials to Treat
Traumatic Brain Injury and Stroke; Challenges in Using Biomarkers in
Central Nervous System Applications; Resolving Difficult Case Scenarios by
Incorporating Stroke Biomarkers in Clinical Decision-making; Development of
Novel Test Platforms for the Assessment of Brain Injury; Advancements and
Challenges in Hyperacute Stroke Translational Research