Anissa Zaouak, Houda Hammami, Samy Fenniche

Acute generalized exanthematous pustulosis

Toxidermia

• Broschiertes Buch

Produktbeschreibung

Acute generalized exanthematous pustulosis (AGEP) is a rare form of toxidermia, one of the severe cutaneous adverse drug reactions (SCAR). It is a febrile, erythematous, putular cutaneous reaction, most often caused by drugs. It may also be due to a viral infection (enterovirus: coxsackie, echovirus or cytomegalovirus), a toxic substance (mercury) or a food allergen. All ages are concerned. The drugs most often responsible are antibiotics such as beta-lactams and pristinamycin. PEAG is a model of delayed drug hypersensitivity mediated by CD8 T lymphocytes. The onset of this toxidermia is short, ranging from a few hours to a few days. Diagnosis of this dermatosis is based on clinical and para-clinical criteria. These criteria were validated by a score, established in 2001 by the European SCAR study group (EuroSCAR).Clinically, PEAG manifests as a bright red, sometimes scarlatiniform, edematous erythema, undertaking the trunk, limbs, and more particularly the axillary and inguinal folds.

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Produktdetails

• Verlag: Our Knowledge Publishing
• Seitenzahl: 52
• Erscheinungstermin: 3. September 2024
• Englisch
• Abmessung: 220mm x 150mm x 4mm
• Gewicht: 96g
• ISBN-13: 9786208041953
• ISBN-10: 6208041953
• Artikelnr.: 71515472

Autorenporträt

Dr. Anissa Zaouak is an associate professor of dermatology with a specialization in allergology and toxidermia.