Addiction and Brain Damage

Herausgeber: Richter, Derek

• Broschiertes Buch

Produktbeschreibung

Originally published in 1980, recent research had produced new insights into how, at the biochemical level, alcohol and other drugs of abuse can impair metabolic and neuropsychiatric functions. Epidemiological studies were also demonstrating that even moderate drinking or drug abuse can produce significant brain damage. This book draws together the latest biochemical, physiological and clinical research on these topics at the time. The initial chapters discuss how alcohol can interfere with various functions: the adaptability of metabolic processes as governed by the ability of the liver to synthesise new enzymes, cell membrane transport, nervous transmission and the transport of nutrients into the brain. It is suggested that opiates, and possibly alcohol, may affect the endorphin system by blocking the uptake of specific amino acids. The second half of the book reports clinical investigations using biochemical studies, psychological tests, EEG investigations and Computerised Axial Tomography (CAT) scanning. It gives the first report of a long-term study by Lishman and co-workers using an improved tomography technique to assess brain damage in alcoholics. These studies give convincing evidence that heavy drinking, even at socially-acceptable levels, can cause serious brain damage in vulnerable people.

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Produktdetails

• Verlag: Routledge
• Seitenzahl: 308
• Erscheinungstermin: 18. September 2018
• Englisch
• Abmessung: 234mm x 156mm x 17mm
• Gewicht: 471g
• ISBN-13: 9781138210936
• ISBN-10: 1138210935
• Artikelnr.: 54925492

Autorenporträt

Derek Richter

Inhaltsangabe

Preface. Part 1: Biochemical and Physiological Mechanisms 1. The Effects of
Alcohol on Metabolic Processes Hans Krebs 2. Catecholamine-derived
Alkaloids in Dependence Virginia E. Davis, Jesse L. Cashaw and Kenneth D.
McMurtrey 3. The Effects of Alcohol on the Cell Membrane: A Possible Basis
for Tolerance and Dependence John M. Littleton 4. Metabolic Aspects of
Ethanol Dependence and Tissue Damage Marie E. Bardsley and Keith F. Tipton
5. The Transport of Nutrients into the Brain: The Effect of Alcohol on
their Supply and Utilisation Oliver E. Pratt 6. Anomolies in the Function
of Dopamine Systems in Ethanol-withdrawn Animals B. Tabakoff, S. Urwyler
and P.L. Hoffman 7. Opioid Peptides: Their Role in Drug Dependence Albert
Herz Part 2: Clinical Investigations 8. The Effects of Ethanol on the
Endocrine System Vincent Marks 9. Impairments of the Nervous System in
Alcoholics Vladimir Hudolin 10. Computed Tomography of the Brain and
Neuropsychological Assessment of Male Alcoholic Patients Hans Bergman,
Stefan Borg, Thomas Hindmarsh, Carl-Magnus Ideström and Sture Mützell 11.
Computed Tomography of the Brain and Psychometric Assessment of Alcoholic
Patients - A British Study W.A. Lishman, M. Ron and W. Acker 12. Activity
of Monoamines Oxidase and Brain Levels of Monoamines in Alcoholics C.G.
Gottfries 13. Biochemical and CEEG Investigation of Drug Addicts:
Preliminary Findings M. Del Vecchio, L. Vacca, F. Marciano, G. Nolfe, G.
Iorio, M. Maj and D. Kemali 14. Vitamin Status in Brain-damaged Chronic
Alcoholics Allan D. Thomson, S.A. Rae and A. Rowe 15. Brain Damage in
Chronic Alcoholics: A Review of the Psychological Evidence Ralph E. Tarter
16. Conclusion G.K. Shaw. Notes of Contributors. Index.