The publication of the book "ADVANCED PRACTICAL ORGANIC CHEMISTRY" endeavors to afford a comprehensive set of experiments in practical organic chemistry, which will be appropriate for both undergraduate and postgraduate chemistry students, which are normally described in the university syllabi.The present book divided into four chapters, Chapter-I convey the introductory aspects of the organic chemistry laboratory which include Safety rules, Instructions, Terminology & Definitions, Purification techniques, flow chart for organic synthesis, and instrumental video materials.A special feature of this book is that the preparations and covers the preparations of organic compounds include conventional (single and multi-stage preparations) and green synthesis approach which includes microwave-assisted, sonochemistry, phase transfer catalysts, and biocatalysis, etc., have been illustrated in Chapter II. It also depicted preparations of some miscellaneous compounds, as well as some special types of compounds such as drugs, heterocycles, polymers, indicators, dyes, and macromolecules.