Advances in Myocardiology

Volume 4
Herausgegeben:Chazov, Eugene I.

• Broschiertes Buch

Produktbeschreibung

This volume of Advances in Myocardiology is derived from a part of the proceedings of the 10th Congress of the International Society for Heart Research, which was held in Moscow on September 23-29, 1980. This book contains selected papers which have been arranged in two sections, Cardiac Hypertrophy, Adaptation, and Pathophysiology and Cardiac Hypoxia, Is chemia, and Infarction. The first section, on the pathophysiology of heart hypertrophy and failure, contains 24 chapters that focus on the derangement of biochemical, physiological, and immunological processes during the de velopment of heart disease due to a wide variety of pathogenic factors. Some of the recent developments in understanding the myocardial synthetic ma chinery in heart hypertrophy are also described in these papers, and we believe that the contents of this section will stimulate further research in the area of heart disease. The second section, which mainly deals with myocardial ischemia, contains 35 chapters providing the necessary back ground for the diagnosis of ischemic heart disease and some possible ther apeutic approaches. It hardly needs to be emphasized that ischemic heart disease is a major cause of death in highly industrialized countries, but unfortunately the exact mechanism by which ischemic insult leads to the development of heart cell damage is far from understood. We are hopeful that the articles in this section will provide valuable information in this field and thus will help in improving the treatment of ischemic heart disease.

Produktdetails

• Verlag: Springer / Springer US / Springer, Berlin
• Artikelnr. des Verlages: 978-1-4757-4443-9
• Softcover reprint of the original 1st ed. 1983
• Seitenzahl: 664
• Erscheinungstermin: 5. März 2013
• Englisch
• Abmessung: 254mm x 178mm x 36mm
• Gewicht: 1228g
• ISBN-13: 9781475744439
• ISBN-10: 1475744439
• Artikelnr.: 39566051

Inhaltsangabe

Cardiac Hypertrophy, Adaptation, and Pathophysiology.- Pathogenesis and Prophylaxis of Cardiac Lesions in Stress.- Energy Metabolism of the Heart in Catecholamine-Induced Myocardial Injury: Concentration-Dependent Effects of Epinephrine on Enzyme Release, Mechanical Function, and "Oxygen Wastage".- The Permissive Role of Catecholamines in the Pathogenesis of Hamster Cardiomyopathy.- Adaptive and Pathological Alterations in Experimental Cardiac Hypertrophy.- Reflections on What Makes the Heart Grow.- Force-Velocity-Length Relationship during Cardiac Hypertrophy: Time Course of Activation.- Hemodynamics, Regional Myocardial Blood Flow, and Sarcoplasmic Reticulum Calcium Uptake in Right Ventricular Hypertrophy and Failure.- Myocardial Energy Metabolism of Congestive and Hypertrophic Cardiomyopathy in Man.- Effects of Cardiac Work and Leucine on Protein Turnover.- The Rate of Cardiac Structural Protein Synthesis in Perfused Heart.- DNA Synthesis and Mitotic Activity in Adult Atrial Cardiocytes in Culture.- DNA Synthesis in Atrial Myocytes of Rats with Aortic Stenosis.- DNA Synthetic Activity of Right and Left Ventricular Biopsy Specimens in Patients with Cardiomyopathy.- Comparative Changes in the 32P Labeling of Adenine and Uracil Nucleotides in the Hypertrophying Rat Heart.- Increased Synthesis of the Phosphorylated Form of the Myosin Light Chains in Cardiac Hypertrophy in the Rat.- Reconstitution of Heavy Chain and Light Chain 1 in Cardiac Subfragment-1 from Hyperthyroid and Euthyroid Rabbit Hearts.- Mechanisms of Degradation of Myofibrillar and Nonmyofibrillar Protein in Heart.- Vasoactive Peptides and Regulation of Hemodynamics in Different Functional States of the Organism.- Pathogenesis of Immune-Mediated Carditis in Monkeys.- Immunologic Studies in InfectiveEndocarditis.- Adaptation of the Organism during Long-Lasting Survival with a Total Artificial Heart.- A Possible Mechanism of Adriamycin Cardiotoxicity: Inhibition of NADP-Linked Isocitrate Dehydrogenase.- Effects of Propranolol and Hydrocortisone Pretreatment on Radiation-Induced Myocardial Injury in Rats.- Inhibition of Vitamin D3-Induced Vascular Calcification by Carbocromen.- Cardiac Hypoxia, Ischemia, and Infarction.- Mitochondrial Function in Normal and Hypoxic States of the Myocardium.- Cardiac Synthesis and Degradation of Pyridine Nucleotides and the Level of Energy-Rich Phosphates Influenced by Various Precursors.- Effect of Exogenous Amino Acids on the Contractility and Nitrogenous Metabolism of Anoxic Heart.- Regulation of Cardiac Contractility and Glycolysis by Cyclic Nucleotides during Hypoxia.- Hypoxia, Calcium, and Contracture as Mediators of Myocardial Enzyme Release.- Cyclic AMP and Early Contractile Failure.- Release of Purine Nucleosides and Oxypurines from the Isolated Perfused Rat Heart.- Pathophysiology of Irreversible Ischemic Injury: The Border Zone Controversy.- Acid Hydrolases in the Initiation of Ischemic Myocardial Necrosis.- Release of Prostacyclin into the Coronary Venous Blood in Patients with Coronary Arterial Disease.- The Effects of Systole on Left Ventricular Blood Flow.- Prolonged Depletion of ATP Because of Delayed Repletion of the Adenine Nucleotide Pool following Reversible Myocardial Ischemic Injury in Dogs.- Cytochrome Oxidase Activity of Mitochondria from Ischemic and Reperfused Myocardium.- The Effect of Experimentally Induced Myocardial Ischemia on the Norepinephrine Metabolism of the Dog Heart.- Reperfusion Injury: A Possible Link between Catecholamine-Induced and Ischemic Myocardial Alterations.- Ultrastructural, Functional, and Metabolic Correlates in the Ischemic Rat Heart: Effects of Free Fatty Acid.- Detection of Intracellular Anoxia and Its Relationship to Onset of Hemodynamic Dysfunction and ST-Segment Elevation in the Intact Dog Heart.- The Relationship between Glucose Utilization during Ischemia and Ventricular Fibrillation during Early Reperfusion: Evidence for Two Populations of Guinea Pig Hearts.- Correlation among Water Content, Left Ventricular Function, Coronary Blood Flow, and Myocardial Metabolism after Hypothermic Ischemic Cardiac Arrest.- Serial Changes in Cytosolic, Mitochondrial, and Lysosomal Enzymes and Cardiac Myosin Light Chain II in Plasma following Coronary Ligation in Conscious Closed-Chest Dogs.- Myosin Light Chain Phosphorylation during Regional Myocardial Ischemia.- Myocardial Infarct Size from Serum Cardiac Myosin Light Chain: Clinical and Experimental Studies.- Biopsy Assessment of Preservation during Open-Heart Surgery with Cold Cardioplegic Arrest.- Calcium Antagonistic Activity and Myocardial Ischemic Protection by Both Stereoisomers of Verapamil.- The Effects of ? Blockade and Partial Agonist Activity during Myocardial Ischemia.- Cyclic Nucleotides and Changes in Protein Kinase Activity Ratio in the Ischemic and Nonischemic Myocardium.- Myocardial Biosynthesis of Prostaglandins with Special Consideration of Prostacyclin and the Influence of Dipyridamole and Propranolol.- Influence of Cardiovascular Drugs on Platelet Aggregation.- Effects of L-Carnitine on Tissue Levels of Free Fatty Acid, Acyl CoA, and Acylcarnitine in Ischemic Heart.- Effect of Coenzyme Q10 on Hypertrophied Ischemic Myocardium during Aortic Cross Clamping for 2 hr, from the Aspect of Energy Metabolism.- Preservation of Oxidative Phosphorylation by Lidocaine in Ischemic and ReperfusedMyocardium.- On the Mechanism of Action of the Antianginal Drug Nonachlazine on Ischemic Myocardium.- Studies on Slow Cardiac Action Potentials Occurring in Potassium-Rich Media as a Simulation of the Early Phase of Myocardial Infarction: Influence of Potassium-Conductance Blockers and Antiarrhythmic Drugs.- Antiischemic Effects of Molsidomine in an Experimental Model of Coronary Model of Coronary Artery Stenosis.- Effect of Molsidomine on Spontaneous Ventricular Fibrillation following Myocardial Ischemia and Reperfusion in the Dog.- Contributors.