Human skin acts as an excellent barrier to infection, provided it is not breached (Bhatt et al., 2007). Exposure of subcutaneous tissue following a loss of skin integrity (i.e. a wound) provides moist, warm, and nutritious environment that is conducive to microbial colonization and proliferation. However, the abundance and diversity of microorganisms in any wound will be influenced by factors such as wound type, depth, location, and quality, the level of tissue perfusion, and the antimicrobial efficacy of the host immune response (Bowler et al., 2001).