Aging

Exploring a Complex Phenomenon
Herausgeber: Ahmad, Shamim I.

• Broschiertes Buch

Produktbeschreibung

This book is a detailed and comprehensive synthesis of the scientific study of aging. Dozens of contributions from leading scholars review various theories of aging, and molecular, cellular, biochemical and microbial aspects of aging, among just a few of the topics included. Authoritative, wide ranging and thorough, this book will act as a source for experimental design, a comprehensive description of age related diseases, and provide information of the latest molecular theories underlying their causes. Additionally, it will target industries involved in developing anti-aging drugs, post-graduate medical students, and university libraries.

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Produktdetails

• Verlag: CRC Press
• Seitenzahl: 684
• Erscheinungstermin: 30. März 2021
• Englisch
• Abmessung: 246mm x 189mm x 36mm
• Gewicht: 1300g
• ISBN-13: 9780367657567
• ISBN-10: 0367657562
• Artikelnr.: 60599608

Autorenporträt

Shamim I. Ahmad received his PhD from Leicester University and has been Lecturer at Nottingham Trent University where he the British Asian Award for "Excellence in Education." He has authored or edited eleven books and dozens of peer reviewed research papers. His research interests are in the field of DNA damage and repair and associated diseases, molecular mechanisms of Fanconi anemia, role of reactive oxygen species (ROS) in health and diseases, skin cancer by sunlight, Anti-AIDS drug development, development of new procedures for treatment of cancer, viral and bacterial infections.

Inhaltsangabe

What is aging. Biological theories of aging. Free radical theory.
Mitochondrial dysfunction theory. Error catastrophe theory. Evolutionary
theory of aging. Fading electricity theory. Quasi-program theory for aging.
Multiple hormone deficiency theory of aging. Oxidation-inflammation theory
of aging. Reproductive-cell cycle theory of aging. Telomeres and telomerase
theory of aging. Markov Models of aging. Immunological theory of aging.
Social theory of aging. Genetic program theory of aging. Psychological
theory of aging. Healthy living and its effects on aging. Longevity in
aging. Impact of climate on aging. Centenarians in Okinawa. Genetics of the
population. Caloric restriction, healthy diet. Staying young at heart.
Genetics of aging and longevity. Metabolic programming, exercise, caloric
restriction and aging. Premature aging. Progeria and Werner's syndrome.
Stem cell aging in progeria. Oxidative and nitrosative stress and
accelerative aging. Progeria: Genetics, and lamin disorder. Molecular
aspect of aging. Hematopoietic stem cells aging. Immune system and aging.
Sirtuins in aging and age related diseases. AMPK function in aging. Aging
mechanisms and lipid changes. Biochemical aspects of aging. GABA(A)
receptors in aging. The ubiquitin-proteasome system and aging. Autophagy
and aging. Oxidation of potassium channels and aging. Proteins and lipids
in aging. Spatial protein quality control and aging. Klotho protein and
aging. Glutathione as antioxidant. Neuropeptide Y as an anti-aging agent.
Adipokines and aging. Lamins and aging. Sestrins and aging. HDL metabolism
and aging. Growth hormone and aging. DNA damage, repair and aging. DNA
damage, repair and neurodegenerative diseases. yH2AX molecular marker for
DNA damage and aging. DNA repair in organelles and aging. Transcriptional
blocking and DNA damage in aging. Microbiota and aging. Neuroscience of
aging. Thermal stress in human and aging. Age related diseases. Ischemic
heart disease and aging. Endothelial and vascular aging. The aging heart.
Age related eye disease. Age related inflammation and osteoarthritis. Aging
and musculoskeletal health. Cancer and aging. Sexual health in aging. Sleep
disturbance in aging. Anxiety in aging. Female sexuality and aging. Aging
and circadian rhythm. Metabolic syndrome and aging. Environmental toxicants
and aging. Stem cell and aging. Non-human models for aging studies. Aging
modulation in multiple species. Mouse models. Murine genetic models. C.
elegans model. S. cerevisiae model. Drosophila model. Pig model. Mammalian
hibernation and aging. Neobiosis as a predecessor of mammalian hibernation.
Chemosensory and chemosensory systems and aging. Molecular biology of
freezing tolerance. Freezing susceptibility in arthropods. Proteomic
approach to study mechanisms of aging. Therapeutic approach for facial
aging. Integrative medicine research on aging population. Meditation and
aging. Life after death: Fact or fiction.