Macro-benthic algae Catenella nipae was cultured from November '06 to August '07 at the Salimpur planted mangrove area of Chittagong Coast, Bangladesh. The bio-chemical composition of the cultured C. nipae and the physico-chemical parameters in the tidal swamp of Salimpur mangrove area were recorded during the culture period . The daily average growth of C. nipae on bamboo poles was recorded 0.19 cm/day. A total of 176 g/m2 biomass of C. nipae were found during the culture period for three months. Physico-chemical parameters of both water and soil revealed that the coastal area of Salimpur could be a significant place for C. nipae cultivation during the monsoon period (June-October) and proximate composition of C. nipae showed the good amount of nutritive value. Therefore, this seaweed may be use for human food and food additives in the local market of Bangladesh. The study was first approach in this region and may be used as baseline reference for commercial culture of seaweeds in Bangladesh.