Allyl isothiocyanate - A Promising drug for Liver Cancer - Subbaraj, Gowtham kumar
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In the present investigation,the efficacy Allyl isothiocyanate(AITC)against N-nitrosodiethylamine induced experimental liver carcinogenesis and in human hepatoma cell line (HepG2)were studied.Cell migration inhibition effect of AITC reveal that the drug has a role in delay of cancer progression . The dose dependent protein expression of P53 and Caspase 3 disclose the anticancer potency of the drug AITC.This was confirmed by various biochemical,molecular biological and histopathological examinations as well.

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Produktbeschreibung
In the present investigation,the efficacy Allyl isothiocyanate(AITC)against N-nitrosodiethylamine induced experimental liver carcinogenesis and in human hepatoma cell line (HepG2)were studied.Cell migration inhibition effect of AITC reveal that the drug has a role in delay of cancer progression . The dose dependent protein expression of P53 and Caspase 3 disclose the anticancer potency of the drug AITC.This was confirmed by various biochemical,molecular biological and histopathological examinations as well.
Autorenporträt
This monograph from the doctoral thesis of the author, Dr.Gowtham kumar Subbaraj.This research work was carried out and the PhD degree was obtained from PGIBMS,University of Madras,Chennai.Currently he is working in Chettinad University,Kelambakkam,Chennai-603 103 as Assistant professor in Genetics.His area of interest is Cancer biology,Angiogenes