In this book, the investigation for the gel extraction by centrifugal action from Aloe Vera leaves is described.This investigation was aimed at standardizing important process parameters with the specific objective of developing an appropriate process technology for extraction of gel from Aloe vera barbadensis. The optimum proportion of acetone, temperature, centrifuge speed and duration was decided on the basis of quality parameters of gel.The effect of acetone, temperature, speed and duration on quality parameters like gel recovery, viscosity of gel,refractive index of gel, optical density of gel, and TSS content of gel were studied. It was concluded that the extraction of gel from Aloe vera should be carried 5 degree Celsius temperatures, 10000 rpm speed and 30 min duration of centrifuge, without addition of acetone to pulp so as to obtain higher gel recovery and good quality of gel.