Alpha Thalassemia and Haplotypes of Beta Globin in Sickle Cell Disease - Rodrigues, Daniela de Oliveira Werneck; Sudário, Lysla Cardoso; Ribeiro, Luiz Claudio
30,99 €
inkl. MwSt.
Versandkostenfrei*
Versandfertig in 1-2 Wochen
payback
15 °P sammeln
  • Broschiertes Buch

Sickle cell disease (DF) is the most common hereditary monogenic disease in Brazil. The term DF includes sickle cell anemia (AF) and pathological conditions in which the hemoglobin S gene is associated with other hereditary hemoglobinopathies such as SC, S/beta0 and S/beta+ thalassemia (S/b), SD Punjab, among others. There is a description of 5 haplotypes of the globine chain cluster (¿S) linked to HbS: Asia, Senegal, Benin, Bantu (CAR) and Cameroon. The DF can also coexist with ¿-talassemias (¿-Tal). The most severe complication in the DF is stroke, which is responsible for 20% of mortality.…mehr

Andere Kunden interessierten sich auch für
Produktbeschreibung
Sickle cell disease (DF) is the most common hereditary monogenic disease in Brazil. The term DF includes sickle cell anemia (AF) and pathological conditions in which the hemoglobin S gene is associated with other hereditary hemoglobinopathies such as SC, S/beta0 and S/beta+ thalassemia (S/b), SD Punjab, among others. There is a description of 5 haplotypes of the globine chain cluster (¿S) linked to HbS: Asia, Senegal, Benin, Bantu (CAR) and Cameroon. The DF can also coexist with ¿-talassemias (¿-Tal). The most severe complication in the DF is stroke, which is responsible for 20% of mortality. The causes and factors that would increase the risk of strokes are not completely known. Several lines of evidence suggest that a genetic signature could influence the development of strokes.
Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Autorenporträt
Hematólogo de la Fundación Hemominas - Brasil . Doctorado en Salud Brasileña por la Universidade Federal de Juiz de Fora. Miembro de la Red Global de Anemia Falciforme. Investigador de los estudios multicéntricos internacionales REDS III y REDS IV sobre la seguridad de las transfusiones en la anemia falciforme.