Alternate biomarkers in predicting CD4+ T cell count in HIV patients - Isiyaku, Abdullahi
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In many resource-poor countries, most facilities do not have cyflow counter for the performance of CD4+ count analysis required for the initiation of antiretroviral therapy. CD4+ T cell count and viral load monitoring are expensive and unavailable to most human immunodeficiency virus (HIV) infected people in Africa. There is a need to have another marker of HIV infection that is less resource demanding. Studies in human immunodeficiency virus infected adults have demonstrated association of total lymphocyte count (TLC)

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Produktbeschreibung
In many resource-poor countries, most facilities do not have cyflow counter for the performance of CD4+ count analysis required for the initiation of antiretroviral therapy. CD4+ T cell count and viral load monitoring are expensive and unavailable to most human immunodeficiency virus (HIV) infected people in Africa. There is a need to have another marker of HIV infection that is less resource demanding. Studies in human immunodeficiency virus infected adults have demonstrated association of total lymphocyte count (TLC) <1200 cell/µl and subsequent disease progression or mortality. This study was carried out to determine the relationship of CD4+ T lymphocyte counts with total lymphocyte count (TLC) and immunoglobulin G (IgG) in HIV- positive on highly active antiretroviral therapy (HAART) naive patients attending Specialist Hospital Sokoto northern region, Nigeria. The study population comprised of 100 adult HIV-positive HAART naive patients aged 19-65 years. The CD4+ T cell counts and these alternate biomarkers of study participants were measured. Spearman's rank order correlation was used for statistical analysis.
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Autorenporträt
Isiyaku est un scientifique de laboratoire médical et associé du Medical Laboratory Science Council of Nigeria. Il est titulaire d'un MSc. Medical Laboratory Science (Immunologie), Associate Medical Laboratory Science (Virologie), BSc. Microbiologie et National Diploma in science Laboratory Technology.