Alzhei... who? - Fymat, Alain L
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It is clear that our approach to identifying the root cause of Alzheimer's disease and curing it has not been successful so far despite decades of research, billions of dollars spent worldwide, 244 experimental drugs developed, and many clinical trials that have failed. What is happening? Have we got the cause of Alzheimer's all wrong? I believe so! Instead of remaining focused on the primary endpoint of a cure, the emphasis had shifted to surrogate endpoints that had not been clinically demonstrated to correlate well with the disease. In this book, I identify the root cause of the disease and…mehr

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Produktbeschreibung
It is clear that our approach to identifying the root cause of Alzheimer's disease and curing it has not been successful so far despite decades of research, billions of dollars spent worldwide, 244 experimental drugs developed, and many clinical trials that have failed. What is happening? Have we got the cause of Alzheimer's all wrong? I believe so! Instead of remaining focused on the primary endpoint of a cure, the emphasis had shifted to surrogate endpoints that had not been clinically demonstrated to correlate well with the disease. In this book, I identify the root cause of the disease and attempt to reorient our approach along a path that I am convinced will be more successful in leading us to a cure. I will provide the outlines of this new approach and even suggest the methodology to be followed. At the same time, I am also hoping to be able to co-opt the support I need from the general public, particularly those already afflicted by the disease or fearing they might succumb to it, as well as their families, friends, and caregivers. For them, I will also try to demystify the disease and describe ways they can do something about it in addition to seeking medical treatment.
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Autorenporträt
DR. ALAIN L. FYMAT is the Founding Chair, current President/CEO, and Institute Professor at the International Institute of Medicine & Science with a previous appointment as Executive Vice President, Chief Operating Officer, and Professor at the Weil Institute of Critical Care Medicine, both Institutes in California, U.S.A. He was formerly Professor of Radiology, Radiological Sciences, Radiation Oncology, Critical Care Medicine, and Physics at several U.S. and European Universities. Earlier, he was Deputy Director (Western Region) of the U.S. Department of Veterans' Affairs, Veterans' Health Administration (Office of Research Oversight). At the Loma Linda Veterans' Affairs Medical Center, he was Scientific Director of the Radiology Service, Director of the Magnetic Resonance Imaging Center and, for a time, Acting Chair of Radiology. Previously, he was also Director of the Division of Biomedical & Biobehavioral Research at the University of California at Los Angeles/Drew University of Medicine & Science. He was also Scientific Advisor to the U.S. National Academy of Sciences, National Research Council, for its postdoctoral programs tenable at the California Institute of Technology and member of the Advisory Board for Research & Development, North Atlantic Treaty Organization (NATO), Advisory Group for Research & Development (AGARD). He is Health Advisor to the American Heart & Stroke Association, Coachella Valley Division, California. He is a member of the New York Academy of Sciences and the European Union Academy of Sciences, and a reviewer for the prestigious UNESCO Newton Prize, United Kingdom. Dr. Fymat's current research interests are currently focused on neurodegenerative diseases, including Huntington's disease among several others.