The book Alzheimer's Disease - Epidemiology, Neuropathology, Neurochemistry, and Clinics is derived from an International Symposium on the occasion of the 125th Anniversary of the Birth of Alois Alzheimer (14.6.1864-19.12.1915). Over the past decade, as the elderly have become the fastest-growing segment of the population in industrialized countries, Alzheimer's disease has emerged as one of the major mental health problems. The contributors to this book represent internationally recognized authorities in the field of dementia and present new information about epidemiology, neuropathology,…mehr
The book Alzheimer's Disease - Epidemiology, Neuropathology, Neurochemistry, and Clinics is derived from an International Symposium on the occasion of the 125th Anniversary of the Birth of Alois Alzheimer (14.6.1864-19.12.1915). Over the past decade, as the elderly have become the fastest-growing segment of the population in industrialized countries, Alzheimer's disease has emerged as one of the major mental health problems. The contributors to this book represent internationally recognized authorities in the field of dementia and present new information about epidemiology, neuropathology, neurochemistry, and clinics in Alzheimer's disease. This book is a rich and valuable up-to-date resource for psychiatrists, neurologists, scientists working in the fields of neuropathology, neurochemistry and molecular genetics, behavioral scientists, family physicians and all who share an interest in understanding and treating the older individual with Alzheimer's disease/dementia. Das Buch Alzheimer's Disease enthält Beiträge international anerkannter Kliniker und Wissenschaftler, die in Kapiteln über Epidemiologie, Neuropathologie, Neurochemie und Klinik den derzeitigen Wissensstand über Alzheimer-Krankheit und damit zusammenhängende Demenzen vermitteln.
Some philosophical aspects of Alzheimer's discovery: an American perspective.- The aging brain and its disorders.- Epidemiology of Alzheimer's disease.- Descriptive and analytic epidemiology of Alzheimer's disease.- A proposed classification of familial Alzheimer's disease based on analysis of 32 multigeneration pedigrees.- Morphology of Alzheimer's disease and related disorders.- Morphology of white matter, subcortical, dementia in Alzheimer's disease.- Morphology of the cerebral cortex in relation to Alzheimer's dementia.- Quantitative investigations of presenile and senile changes of the human entorhinal region.- Neuronal plasticity of the septo-hippocampal pathway in patients suffering from dementia of Alzheimer type.- Morphology of neurofibrillary tangles and senile plaques.- An in vitro model for the study of the neurofibrillary degeneration of the Alzheimer type.- Molecular and cellular changes associated with neurofibrillary tangles and senile plaques.- Brain abnormalities in aged monkeys: a model sharing features with Alzheimer's disease.- Aged dogs: an animal model to study beta-protein amyloidogenesis.- Immunocytochemical and ultrastructural pathology of nerve cells in Alzheimer's disease and related disorders.- Choline-acetyltransferase immunoreactivity in the hippocampal formation of control subjects and patients with Alzheimer's disease.- Calbindin immunoreactive _eurons in Alzheimer-type dementia.- Lactate production and glycolytic enzymes in sporadic and familial Alzheimer's disease.- Impairment of cerebral glucose metabolism parallels learning and memory dysfunctions after intracerebral streptozotocin.- Choline levels, the regulation of acetylcholine and phosphatidylcholine synthesis, and Alzheimer's disease.- Acetylcholinesynthesis and membrane phospholipids.- Hippocampal and cardiovascular effects of muscarinic agents.- Cholinergie and monoaminergic neuromediator systems in DAT. Neuropathological and neurochemical findings.- Alterations in catecholamine neurons in the locus coeruleus in dementias of Alzheimer's and Parkinson's disease.- Tyrosine hydroxylase, tryptophan hydroxylase, biopterin and neopterin in the brains and biopterin and neopterin in sera from patients with Alzheimer's disease.- Postreceptorial enhancement of neurotransmission for the treatment of cognitive disorders.- Excitatory dicarboxylic amino acid and pyramidal neurone neurotransmission of the cerebral cortex in Alzheimer's disease.- The sequence within the two polyadenylation sites of the A4 amyloid peptide precursor stimulates the translation.- Alzheimer-like changes of cortical amino acid transmitters in elderly Down's syndrome.- Characteristics of learning deficit induced by ibotenic acid lesion of the frontal cortex in rats.- Memory loss by glutamate antagonists: an animal model of Alzheimer's disease?.- Convulsant properties of methylxanthines, potential cognitive enhancers in dementia syndromes.- Neurodegenerative diseases: CSF amines, lactate and clinical findings.- Somatostatin-like immunoreactivity and neurotransmitter metabolites in the cerebrospinal fluid of patients with senile dementia of Alzheimer type and Parkinson's disease.- Nerve growth factor in serum of patients with dementia (Alzheimer type).- Neuroendocrine dysfunction in early-onset Alzheimer's disease.- Urinary excretion of salsolinol enantiomers and 1,2-dehydrosalsolinol in patients with degenerative dementia.- Alzheimer's disease - one, two or several?.- Diagnostic criteria of Alzheimer's disease.- Clinicaldiagnosis of Alzheimer's disease: DSM-III-R, ICD-10 - what else?.- Clinical aspects and terminology of dementing syndromes.- Symptoms of depression in the course of multi-infarct dementia and dementia of Alzheimer's type.- Cognitive deterioration and dementia outcome in depression: the search for prognostic factors.- Diagnostic significance of language evaluation in early stages of Alzheimer's disease.- The Alzheimer patient in the family context: how to help the family to cope.- Towards a clinically specific profile of severe senile primary degenerative dementia of the Alzheimer type (PDDAT).- Sequential clinical approach to differential diagnosis of dementia.- Do old patients with Down's syndrome develop premature brain atrophy?.- Results of EEG brain mapping and neuroimaging methods in Senile Dementia of Alzheimer's Typ (SDAT) and Vascular Dementia (VD).- Regulation of EEG delta activity by the cholinergic nucleus basalis.- EEG- and cognitive changes in Alzheimer's disease - a correlative follow-up study.- Decreased hippocampal metabolic rate in patients with SDAT assessed by positron emission tomography during olfactory memory task.- PET criteria for diagnosis of Alzheimer's disease and other dementias.- Oxygen metabolism in the degenerative dementias.- Positron emission tomography for differential diagnosis of dementia: a case of familial dementia.- Comparison between cerebral glucose metabolism and late evoked potentials in patients with Alzheimer's disease.- High resolution regional cerebral blood flow measurements in Alzheimer's disease and other dementia disorders.- Single photon emission computed tomography (SPECT) in Pick's disease: two case reports.- In vivo studies of hippocampal atrophy in Alzheimer's disease.- Outline for theevaluation of nootropic drugs.- Drug treatment of dementia.- Cognitive enhancing properties of antagonist ?-carbolines: new insights into clinical research on the treatment of dementias?.- Long term treatment of SDAT patients with pyritinol.- Listed in Current Contents.
Some philosophical aspects of Alzheimer's discovery: an American perspective.- The aging brain and its disorders.- Epidemiology of Alzheimer's disease.- Descriptive and analytic epidemiology of Alzheimer's disease.- A proposed classification of familial Alzheimer's disease based on analysis of 32 multigeneration pedigrees.- Morphology of Alzheimer's disease and related disorders.- Morphology of white matter, subcortical, dementia in Alzheimer's disease.- Morphology of the cerebral cortex in relation to Alzheimer's dementia.- Quantitative investigations of presenile and senile changes of the human entorhinal region.- Neuronal plasticity of the septo-hippocampal pathway in patients suffering from dementia of Alzheimer type.- Morphology of neurofibrillary tangles and senile plaques.- An in vitro model for the study of the neurofibrillary degeneration of the Alzheimer type.- Molecular and cellular changes associated with neurofibrillary tangles and senile plaques.- Brain abnormalities in aged monkeys: a model sharing features with Alzheimer's disease.- Aged dogs: an animal model to study beta-protein amyloidogenesis.- Immunocytochemical and ultrastructural pathology of nerve cells in Alzheimer's disease and related disorders.- Choline-acetyltransferase immunoreactivity in the hippocampal formation of control subjects and patients with Alzheimer's disease.- Calbindin immunoreactive _eurons in Alzheimer-type dementia.- Lactate production and glycolytic enzymes in sporadic and familial Alzheimer's disease.- Impairment of cerebral glucose metabolism parallels learning and memory dysfunctions after intracerebral streptozotocin.- Choline levels, the regulation of acetylcholine and phosphatidylcholine synthesis, and Alzheimer's disease.- Acetylcholinesynthesis and membrane phospholipids.- Hippocampal and cardiovascular effects of muscarinic agents.- Cholinergie and monoaminergic neuromediator systems in DAT. Neuropathological and neurochemical findings.- Alterations in catecholamine neurons in the locus coeruleus in dementias of Alzheimer's and Parkinson's disease.- Tyrosine hydroxylase, tryptophan hydroxylase, biopterin and neopterin in the brains and biopterin and neopterin in sera from patients with Alzheimer's disease.- Postreceptorial enhancement of neurotransmission for the treatment of cognitive disorders.- Excitatory dicarboxylic amino acid and pyramidal neurone neurotransmission of the cerebral cortex in Alzheimer's disease.- The sequence within the two polyadenylation sites of the A4 amyloid peptide precursor stimulates the translation.- Alzheimer-like changes of cortical amino acid transmitters in elderly Down's syndrome.- Characteristics of learning deficit induced by ibotenic acid lesion of the frontal cortex in rats.- Memory loss by glutamate antagonists: an animal model of Alzheimer's disease?.- Convulsant properties of methylxanthines, potential cognitive enhancers in dementia syndromes.- Neurodegenerative diseases: CSF amines, lactate and clinical findings.- Somatostatin-like immunoreactivity and neurotransmitter metabolites in the cerebrospinal fluid of patients with senile dementia of Alzheimer type and Parkinson's disease.- Nerve growth factor in serum of patients with dementia (Alzheimer type).- Neuroendocrine dysfunction in early-onset Alzheimer's disease.- Urinary excretion of salsolinol enantiomers and 1,2-dehydrosalsolinol in patients with degenerative dementia.- Alzheimer's disease - one, two or several?.- Diagnostic criteria of Alzheimer's disease.- Clinicaldiagnosis of Alzheimer's disease: DSM-III-R, ICD-10 - what else?.- Clinical aspects and terminology of dementing syndromes.- Symptoms of depression in the course of multi-infarct dementia and dementia of Alzheimer's type.- Cognitive deterioration and dementia outcome in depression: the search for prognostic factors.- Diagnostic significance of language evaluation in early stages of Alzheimer's disease.- The Alzheimer patient in the family context: how to help the family to cope.- Towards a clinically specific profile of severe senile primary degenerative dementia of the Alzheimer type (PDDAT).- Sequential clinical approach to differential diagnosis of dementia.- Do old patients with Down's syndrome develop premature brain atrophy?.- Results of EEG brain mapping and neuroimaging methods in Senile Dementia of Alzheimer's Typ (SDAT) and Vascular Dementia (VD).- Regulation of EEG delta activity by the cholinergic nucleus basalis.- EEG- and cognitive changes in Alzheimer's disease - a correlative follow-up study.- Decreased hippocampal metabolic rate in patients with SDAT assessed by positron emission tomography during olfactory memory task.- PET criteria for diagnosis of Alzheimer's disease and other dementias.- Oxygen metabolism in the degenerative dementias.- Positron emission tomography for differential diagnosis of dementia: a case of familial dementia.- Comparison between cerebral glucose metabolism and late evoked potentials in patients with Alzheimer's disease.- High resolution regional cerebral blood flow measurements in Alzheimer's disease and other dementia disorders.- Single photon emission computed tomography (SPECT) in Pick's disease: two case reports.- In vivo studies of hippocampal atrophy in Alzheimer's disease.- Outline for theevaluation of nootropic drugs.- Drug treatment of dementia.- Cognitive enhancing properties of antagonist ?-carbolines: new insights into clinical research on the treatment of dementias?.- Long term treatment of SDAT patients with pyritinol.- Listed in Current Contents.
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