This book will focus on new molecular interactions and novel activities and the associated diseases that have been recently discovered from the studies of eukaryotic and mammalian aminoacyl-tRNA synthetases. In addition, the potential applications of ARS researches in biotechnology and medicine will be addressed.
This book will focus on new molecular interactions and novel activities and the associated diseases that have been recently discovered from the studies of eukaryotic and mammalian aminoacyl-tRNA synthetases. In addition, the potential applications of ARS researches in biotechnology and medicine will be addressed.
1983-1986 Researcher, Genetic Eng. Center, KAIST, Korea 1991-1994 Post-doc, MIT, USA 1993-1994 Senior Scientist, Cubist Pharmaceuticals, USA 1994-2001 Associate Professor, Sung Kyun Kwan University, Korea 2001-present Professor, College of Pharmacy, Graduate Program in Bioinformatics , Genetic Engineering, Cancer Biology, Seoul National Univ. 1998-present Director, Center for Medicinal Protein Network and Systems Biology, Seoul National University 2008- Director, Information Center of Bio-pharmacological Network 2008- Director, Integrated Bioscience and Biotechnology Institute
Inhaltsangabe
Catalysis.- Emergence and Evolution.- Architecture.- Protein-protein Interactions and Multicomponent Complexes.- Interactions with RNAs.- Secretion and Circulation.- Regulatory Roles.- Neural Diseases.- Cancer.- Immune Diseases.- Pathologic Implications of Mitochondrial tRNA Synthetases .- Infectious Diseases.- Reprogramming of Genetic Code.- Novel functions of tRNAs.- Perspectives for Systems and Synthetic Bio-Medicine.
Catalysis.- Emergence and Evolution.- Architecture.- Protein-protein Interactions and Multicomponent Complexes.- Interactions with RNAs.- Secretion and Circulation.- Regulatory Roles.- Neural Diseases.- Cancer.- Immune Diseases.- Pathologic Implications of Mitochondrial tRNA Synthetases .- Infectious Diseases.- Reprogramming of Genetic Code.- Novel functions of tRNAs.- Perspectives for Systems and Synthetic Bio-Medicine.
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