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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Amyotrophic lateral sclerosis is the most common disease of motor neuron system. The condition is also known as Charcot disease and Lou Gehrig's disease and it is caused by the degeneration of neurons and leads to muscle weakness, gradually depriving affected individuals of their ability to carry out everyday tasks and activities, eventually leaving them wheelchair-bound. Learn more about the disease, its causes and treatment in this book.