Amyotrophic Lateral Sclerosis

Herausgeber: Mitsumoto, Hiroshi; Gordon, Paul H.; Przedborski, Serge

• Broschiertes Buch

Produktbeschreibung

With cutting-edge contributions from internationally recognized experts and field pioneers, Amyotrophic Lateral Sclerosis is the definitive guide to the subject. Formatted in an easily accessible manner, with summaries of key points at the end of each chapter, this guide covers all the essential information clinicians require for daily practice, as well as providing a reader-friendly approach to every aspect of ALS with detailed sections on the clinical features of disease, translational research, patient care and management, and emerging therapies.

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Produktdetails

• Verlag: CRC Press
• Seitenzahl: 872
• Erscheinungstermin: 17. Oktober 2019
• Englisch
• Abmessung: 254mm x 178mm x 46mm
• Gewicht: 1605g
• ISBN-13: 9780367391843
• ISBN-10: 0367391848
• Artikelnr.: 58055915

Autorenporträt

Hiroshi Mitsumoto, Serge Przedborski, Paul H. Gordon

Inhaltsangabe

Overview of Clinical ALS. History. Epidemiology. Pathology. Clinical
Features: Motor System. Clinical Features: Dementia and Cognitive Deficits.
Familial ALS and Genetic Approaches to ALS. Electrophysiology and Other
Objective Markers. Classification, Diagnosis and Presentation of Diagnosis
of ALS. Natural History. Translational Research in ALS: Mechanisms behind
therapy. Motor Neuron: The origin, definition and function.
Neurodegeneration. Excitotoxicity. Oxidative Stress. Neuroinflammation.
Apoptosis. Cytoskeleton. Mitochondria. Environmental Neurotoxicity. Genetic
Causes and Predisposition. Protein Aggregate Disease. Proteiomic and
Metabolomic Approach.
Infections and Autoimmunity. Gene Transfer Technology. High Through-put
Technology. Animal Models. Restoration-Practical Approach. Clinical Trial
Methodology. ALS Therapy: Care and Management. Multidisciplinary Approach:
Ideal Care Centers and World Perspective. Impact of National ALS Care
Database and Practice Parameters. Symptomatic Pharmacotherapy: Bulbar and
Constitutional Symptoms. Pharmacotherapy: In clinical trials. Physical
Rehabilitation. Speech Therapy and Augmentative Communication/Assistive
Technology. Nutritional treatment: Theoretical and Practical issues.
Respiratory care: Basic and Practical. Psychosocial care: Patient and
Caregiver Support. Palliative Care. Palliative Care: Family Perspective.
Decision Making for End of Life. National ALS Study Group: Future of ALS
Clinical Research