The present work reviewed exergy analysis which is used mainly in desiccant based hybrid thermal cooling cycles for calculating exergy losses which occur in various components used in the system like a dehumidifier, regenerative heater, sensible cooler, etc. Based on the same the preventive measures can be suggested to reduce exergy destructions in the system. It is found that the exergy losses in desiccant cooling depend mainly on the regeneration temperature to reactivate the desiccant used in the dehumidifier. Earlier research discovered that out of many components used in the hybrid cooling system, exergy destruction occurs highest in the rotary dehumidifier. The use of desiccants in a dehumidifier that regenerates at nearly ambient temperature tends to reduce exergy losses in the hybrid cooling system. The previous results also show that the solid desiccant dehumidification integrated vapor-compression based hybrid cooling technique can be efficiently used for air-conditioning in a typical hot and humid climate and exergy performance of the system can be ameliorated by using freely available renewable solar heat.