On 800 pages this textbook provides students and professionals in life sciences, pharmacy and biochemistry with all they need to know about molecular biotechnology. A very detailed introduction to the fundamentals of molecular and cell biology is followed by an overview of standard techniques applied in molecular biotechnology. The third part then focuses on the key topics, ranging from proteomics and bioinformatics to drug targeting, structural biology, gene therapy and knock mice. The whole is rounded off by a section on biotechnology in industry patenting issues, company foundation and market opportunities.
Written by exceptionally experienced experts from one of the world's major biotech regions, the Heidelberg area, the authors come from academia, such wellknown research centers as the German Cancer Research Center, and biotech companies. A very detailed introduction to the fundamentals in molecular and cell biology is followed by an overview of standard techniques applied in molecular biotechnology including chromatography and electrophoresis, cloning techniques, gene expression systems, immunological methods, labeling of proteins and in situtechniques, microscopy and laser systems. The third part then focuses on the key topics of molecular biotechnology, ranging from functional genomics, proteomics and bioinformatics to drug targeting, recombinant antibodies, structural biology, gene therapy and knock mice. The whole is rounded off by a section on biotechnology in industry dealing with patenting issues, company foundation and market opportunities. Over 800 pages this book provides students and professionals in life sciences, pharmacy and biochemistry with all they need to know about molecular biotechnology.Die Molekulare Biotechnologie ist ein sehr junger Zweig der Naturwissenschaften und verknüpft die Fachgebiete Molekulare Genetik, Bioinformatik, Mikrobiologie, Zellbiologie und Biochemie mit der Bioverfahrenstechnik. Studierende des Studienganges Molekulare Biotechnologie haben die Möglichkeit, interdisziplinär den Einsatz und die gezielte Nutzung biologischer Prozesse von Organismen und Zellen zu erlernen und für neue Fragestellungen, wie beispielsweise die Entwicklung von neuen pharmazeutischen Wirkstoffen oder biologischen Werkstoffen, anzuwenden. In dem vorliegenden Lehrbuch vermittelt das aus erfahrenen Spezialisten bestehende Autorenteam aktuelles Grundlagenwissen aus Proteomik, funktioneller Genomik und moderner WirkstoffForschung. Das besondere Interesse gilt dabei wichtigsten Methoden und neuesten Technologien aus Forschung und biotechnischer Produktion. Das Lehrbuch wendet sich sowohl an Studierende im Grund und Aufbaustudium des Studienganges Molekulare Biotechnologie als auch an Studierende in etablierten Studiengängen der Pharmazie, Biologie, Biochemie und Chemie. Es ist darüber hinaus ein wichtiges Nachschlagewerk für Diplomanden, Doktoranden und technisches Personal in biotechnologischen Labors. Das erfahrene Autorenteam dieses Lehrbuches bietet ein einzigartiges Themenspektrum von molekularbiologischen und biotechnischen Methoden über Strategien der Wirkstoffentwicklung bis hin zu Informationen über Patentrecht, Firmengründung und die moderne BiotechBranche.
Aus dem Inhalt:
I INTRODUCTION Fundamentals of Molecular and Cell Biology II STANDARD METHODS IN MOLECULAR BIOTECHNOLOGY Chromatography and Electrophoresis Enzymes for Modification of Nucleic Acids and Proteins DNA/RNA Isolation Nucleic Acids Hybridisation PCR DNA Sequencing Cloning Techniques Gene Expression Protein Isolation and Separation Techniques Immunological Methods Labeling of Proteins and in situTechniques Electrophysiology Cell Cycle Measurements Microscopy Lasersystems, Fluorescens Intracellular Lokalisation Single Molecule Spectroscopy III Key Topics Genomics Funktional Genomics Proteomics ProteinProtein und ProteinNucleic Acids Interactions Bioinformatics Drug Development Drug Targetting Structural Biology Recombinant Antibodies Phage Display Diagnostics Macromolecular Drugs Knockout Mice Gene Therapy PNAs, RNA/DNADerivatives Katalytic RNAs Katalytic Processes; Enzyme Technology 'Classical' Biotechnology IV BIOTECHNOLOGY IN INDUSTRY Opportunities, Risks and Public Acceptance Patenting Issues BiotechIndustry: Market and Opportunities Marketing Company Foundation
Written by exceptionally experienced experts from one of the world's major biotech regions, the Heidelberg area, the authors come from academia, such wellknown research centers as the German Cancer Research Center, and biotech companies. A very detailed introduction to the fundamentals in molecular and cell biology is followed by an overview of standard techniques applied in molecular biotechnology including chromatography and electrophoresis, cloning techniques, gene expression systems, immunological methods, labeling of proteins and in situtechniques, microscopy and laser systems. The third part then focuses on the key topics of molecular biotechnology, ranging from functional genomics, proteomics and bioinformatics to drug targeting, recombinant antibodies, structural biology, gene therapy and knock mice. The whole is rounded off by a section on biotechnology in industry dealing with patenting issues, company foundation and market opportunities. Over 800 pages this book provides students and professionals in life sciences, pharmacy and biochemistry with all they need to know about molecular biotechnology.
Written by exceptionally experienced experts from one of the world's major biotech regions, the Heidelberg area, the authors come from academia, such wellknown research centers as the German Cancer Research Center, and biotech companies. A very detailed introduction to the fundamentals in molecular and cell biology is followed by an overview of standard techniques applied in molecular biotechnology including chromatography and electrophoresis, cloning techniques, gene expression systems, immunological methods, labeling of proteins and in situtechniques, microscopy and laser systems. The third part then focuses on the key topics of molecular biotechnology, ranging from functional genomics, proteomics and bioinformatics to drug targeting, recombinant antibodies, structural biology, gene therapy and knock mice. The whole is rounded off by a section on biotechnology in industry dealing with patenting issues, company foundation and market opportunities. Over 800 pages this book provides students and professionals in life sciences, pharmacy and biochemistry with all they need to know about molecular biotechnology.Die Molekulare Biotechnologie ist ein sehr junger Zweig der Naturwissenschaften und verknüpft die Fachgebiete Molekulare Genetik, Bioinformatik, Mikrobiologie, Zellbiologie und Biochemie mit der Bioverfahrenstechnik. Studierende des Studienganges Molekulare Biotechnologie haben die Möglichkeit, interdisziplinär den Einsatz und die gezielte Nutzung biologischer Prozesse von Organismen und Zellen zu erlernen und für neue Fragestellungen, wie beispielsweise die Entwicklung von neuen pharmazeutischen Wirkstoffen oder biologischen Werkstoffen, anzuwenden. In dem vorliegenden Lehrbuch vermittelt das aus erfahrenen Spezialisten bestehende Autorenteam aktuelles Grundlagenwissen aus Proteomik, funktioneller Genomik und moderner WirkstoffForschung. Das besondere Interesse gilt dabei wichtigsten Methoden und neuesten Technologien aus Forschung und biotechnischer Produktion. Das Lehrbuch wendet sich sowohl an Studierende im Grund und Aufbaustudium des Studienganges Molekulare Biotechnologie als auch an Studierende in etablierten Studiengängen der Pharmazie, Biologie, Biochemie und Chemie. Es ist darüber hinaus ein wichtiges Nachschlagewerk für Diplomanden, Doktoranden und technisches Personal in biotechnologischen Labors. Das erfahrene Autorenteam dieses Lehrbuches bietet ein einzigartiges Themenspektrum von molekularbiologischen und biotechnischen Methoden über Strategien der Wirkstoffentwicklung bis hin zu Informationen über Patentrecht, Firmengründung und die moderne BiotechBranche.
Aus dem Inhalt:
I INTRODUCTION Fundamentals of Molecular and Cell Biology II STANDARD METHODS IN MOLECULAR BIOTECHNOLOGY Chromatography and Electrophoresis Enzymes for Modification of Nucleic Acids and Proteins DNA/RNA Isolation Nucleic Acids Hybridisation PCR DNA Sequencing Cloning Techniques Gene Expression Protein Isolation and Separation Techniques Immunological Methods Labeling of Proteins and in situTechniques Electrophysiology Cell Cycle Measurements Microscopy Lasersystems, Fluorescens Intracellular Lokalisation Single Molecule Spectroscopy III Key Topics Genomics Funktional Genomics Proteomics ProteinProtein und ProteinNucleic Acids Interactions Bioinformatics Drug Development Drug Targetting Structural Biology Recombinant Antibodies Phage Display Diagnostics Macromolecular Drugs Knockout Mice Gene Therapy PNAs, RNA/DNADerivatives Katalytic RNAs Katalytic Processes; Enzyme Technology 'Classical' Biotechnology IV BIOTECHNOLOGY IN INDUSTRY Opportunities, Risks and Public Acceptance Patenting Issues BiotechIndustry: Market and Opportunities Marketing Company Foundation
Written by exceptionally experienced experts from one of the world's major biotech regions, the Heidelberg area, the authors come from academia, such wellknown research centers as the German Cancer Research Center, and biotech companies. A very detailed introduction to the fundamentals in molecular and cell biology is followed by an overview of standard techniques applied in molecular biotechnology including chromatography and electrophoresis, cloning techniques, gene expression systems, immunological methods, labeling of proteins and in situtechniques, microscopy and laser systems. The third part then focuses on the key topics of molecular biotechnology, ranging from functional genomics, proteomics and bioinformatics to drug targeting, recombinant antibodies, structural biology, gene therapy and knock mice. The whole is rounded off by a section on biotechnology in industry dealing with patenting issues, company foundation and market opportunities. Over 800 pages this book provides students and professionals in life sciences, pharmacy and biochemistry with all they need to know about molecular biotechnology.