Analytical Method development by Liquid Chromatography - Sahu, Prafulla Kumar;Mathrusri Annapurna, M.
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Analytical methods development and validation play important roles in the discovery, development, and manufacture of pharmaceuticals. The current good manufacturing practice (cGMP) and Food Drug Administration (FDA) Guidelines insist for adoption of sound methods of analysis with greater sensitivity and reproducibility. This thesis describes analytical methods developed for drug determination in pharmaceutical dosage forms and biological matrixes including Chromatography (RP-HPLC) and Hyphenated Techniques (LC-MS/MS). Methods have been developed for separation and quantification of selected…mehr

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Produktbeschreibung
Analytical methods development and validation play important roles in the discovery, development, and manufacture of pharmaceuticals. The current good manufacturing practice (cGMP) and Food Drug Administration (FDA) Guidelines insist for adoption of sound methods of analysis with greater sensitivity and reproducibility. This thesis describes analytical methods developed for drug determination in pharmaceutical dosage forms and biological matrixes including Chromatography (RP-HPLC) and Hyphenated Techniques (LC-MS/MS). Methods have been developed for separation and quantification of selected drugs from categories like Antihypertensive, Antihyperlipidemic, Skeletal Muscle Relaxant, Non-Steroidal Anti-inflammatory Drug (NSAID), Antibiotic, Anticonvulsant, Antiviral, and Analeptic.
Autorenporträt
This book has arisen from a series of analytical methodsdeveloped by Prafulla Kumar Sahu and submitted to BerhampurUniversity, for partial fulfillment of his Ph. D. He wasgraduated from K.L.E.S¿ College of Pharmacy and post graduationfrom Roland Institute of Pharmaceutical Sciences.He is a verysuccessful academic teacher and researcher.