The study entitled "Anatomical Exploration of the Sites of Vedhya Siras of the Upper Limb as described by Acharya Sushruta." comprises of introduction, Ayurvedic review, modern review, review of diseases and Marma, cadaveric study and Sira Yantrana, discussion, conclusion and summary. Introduction: - It gives a primary idea about the importance of Sushruta Samhita in the context of anatomical and surgical knowledge. Types of Raktamokshana are described and the importance of Siravedhana as a Raktamokshana therapy is established. It gives an outline of need of study, aims and objectives, materials and methods. Review of Literature: - Both the Ayurvedic and modern reviews deals with the origin, structure and function of Sira. Siravedhana Karma is completely elucidated as a therapeutic measure. Ayurvedic Review Ayurvedic review comprises three main headings Sira Sharir, Vedhya and Avedhya Sira and Siravedhana Vidhi. Sira Sharir consists, etymology, synonyms, definition, chronology, description and classification of Sira.