Annals of the New York Academy of Sciences, Circulating Nucleic Acids in Plasma and Serum V
Herausgeber: Gahan, Peter; Swaminathan, R.
Annals of the New York Academy of Sciences, Circulating Nucleic Acids in Plasma and Serum V
Herausgeber: Gahan, Peter; Swaminathan, R.
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An accurate, inexpensive, and noninvasive method for the early diagnosis of cancer has been something of a holy grail among cancer researchers, but until recently a method meeting all three criteria has been elusive. Nucleic acids were first discovered in circulation in 1948, but it was not until the 1960s and 70s that patients with autoimmune disease and cancer were discovered to have higher levels of circulating DNA than were detected in in healthy persons. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions,…mehr
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An accurate, inexpensive, and noninvasive method for the early diagnosis of cancer has been something of a holy grail among cancer researchers, but until recently a method meeting all three criteria has been elusive. Nucleic acids were first discovered in circulation in 1948, but it was not until the 1960s and 70s that patients with autoimmune disease and cancer were discovered to have higher levels of circulating DNA than were detected in in healthy persons. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member.
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Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Produktdetails
- Produktdetails
- Verlag: Wiley
- Volume 1137 edition
- Seitenzahl: 352
- Erscheinungstermin: 20. Oktober 2008
- Englisch
- Abmessung: 259mm x 183mm x 20mm
- Gewicht: 748g
- ISBN-13: 9781573317344
- ISBN-10: 1573317349
- Artikelnr.: 35367074
- Verlag: Wiley
- Volume 1137 edition
- Seitenzahl: 352
- Erscheinungstermin: 20. Oktober 2008
- Englisch
- Abmessung: 259mm x 183mm x 20mm
- Gewicht: 748g
- ISBN-13: 9781573317344
- ISBN-10: 1573317349
- Artikelnr.: 35367074
Peter Gahan and R. Swaminathan are the authors of Annals of the New York Academy of Sciences, Volume 1137, Circulating Nucleic Acids in Plasma and Serum V, published by Wiley.
Preface: Peter B. Gahan and R. Swaminathan. Circulating Nucleic Acids in Plasma and Serum: Recent Developments: Peter B. Gahan and R. Swaminathan. Part I. Basic Research:. 1. Metabolic DNA as the Origin of Spontaneously Released DNA?: Peter Gahan
Philippe Anker
and Maurice Stroun. 2. Circulating DNA: Its Origin and Fluctuation: Maniesh van der Vaart and Piet J. Pretorius. 3. The Origin of Elevated Levels of Circulating DNA in Blood Plasma of Premature Newborns: N. O. Tuaeva
Z.I. Abramova and V. V. Sofronov. 4. The Effect of Protein Transport Inhibitors on the Production of Extracellular DNA: Evgeniy S. Morozkin
Tatyana I. Babochkina
Valentin V. Vlassov
and Pavel P. Laktionov. 5. Binding and Penetration of Methylated DNA into Primary and Transformed Human Cells: Tatyana E. Skvortsova
Valentin V. Vlassov
and Pavel P. Laktionov. 6. Extracellular DNA Fragments: Factors of Stress Signalling between X-irradiated and Non-irradiated Human Lymphocytes: Aleksei V. Ermakov
Svetlana V. Kostyuk
Marina S. Konkova
Natalya A. Egolina
Elena M. Malinovskaya
and Natalya N. Veiko. 7. Isolation and Sequencing of Short Cell-Surface-Bound DNA: Vera S. Mal'shakova
Dmitry V. Pyshnyi
Alexander A. Bondar
Valentin V. Vlassov
and Pavel P. Laktionov. 8. Extracellular RNA Spontaneously Internalized by Human Cells Undergo Deamination of Adenosines: Elena V. Kuligina
Oksana V. Vratskih
Dmitry V. Semenov
Vera A. Matveea
and Vladimir A. Richter. 9. Circulating Nucleic Acids in the Assessment of Endogenous Growth Hormone Production: H. Thakkar
A.N. Butt
J. Powrie
R. Holt
and R. Swaminathan. 10. The Involvement of Different Mobile Line Copies of Blood Plasma and Extrachromosomal DNA of Liver Cells in Systemic Adaptive Response: Sophiya S. Sherlina and Viktor G. Vladimirov. Part II. Methodology:. 11. Transrenal Nucleic Acids from Proof-of-Principle to Clinical Tests: Problems and Solutions: Hovsep S. Melkonyan
W. John Feaver
Erik Meyer
Vladimir Scheinker
Eugene M. Shekhtman
Zhenghan Xin
and Samuil R. Umansky. 12. Removal of High Molecular Weight DNA by Carboxylated Magnetic Beads Enhances the Detection of Mutated K-ras DNA in Urine: Ying-Hsiu Su
Janet Song
Zhili Wang
Xiao-He Wang
Mengjun Wang
Dean E. Brenner
and Timothy M. Block. 13. A Method for Characterization of Total Circulating DNA: Maniesh van der Vaart and Piet J. Pretorius. 14. Isolation and Extraction of Circulating Tumour DNA from Patients with Small Cell Lung Cancer: Ruth E Board
Victoria S Williams
Lucy Knight
Jacqueline Shaw
Alastair Greystoke
Malcolm Ranson
Caroline Dive
Fiona H Blackhall
and Andrew Hughes. 15. Stability of ß-Actin mRNA in Plasma: N.C. Holford
H.S. Sandhu
H. Thakkar
A.N. Butt
and R. Swaminathan. 16. Normalization of Circulating Nucleic Acid Results. Should We Use ß-Actin?: N.C. Holford
A. Ramoutar
A.N. Butt
and R. Swaminathan. 17. Artificial BOX C/D RNA Targeted to Branch Point Adenosine Impairs Splicing by Exon Exclusion: Dmitry V. Semenov
Oksana V. Vratskih
Elena V. Kuligina
and Vladimir A. Richter. 18. Optimization of Purification of Human Cell-free mRNA from Plasma: Tadeja Dovc-Drnovsek
Barbara Emersic
Primoz Rozman
Darko Cerne
and Jana Lukac-Bajalo. 19. Fragments of Non-coding RNA in Plasma of Human Blood: Dmitry V. Semenov
Dmitry N. Baryakin
Tatyana P. Kamynina
Elena V. Kuligina
and Vladimir A. Richter. 20. An Improved Method for the Isolation of Free-circulating Plasma DNA and Cell-free DNA from Other Body Fluids: Christoph Kirsch
Sabine Weickmann
Bernd Schmidt
and Michael Fleischhacker. Part III. Fetal Nucleic Acids:. 21. Fetal Nucleic Acids in Maternal Plasma: Towards the Development of Noninvasive Prenatal Diagnosis of Fetal Chromosomal Aneuploidies: Y.M. Dennis Lo. 22. Phenotype and mRNA Expression of Syncytiotrophoblast Microparticles Isolated from Human Placenta: Belinda Kumpel
May-Jean King
Suren Sooranna
Dave Jackson
Jane Eastlake
Rong Cheng
and Mark Johnson. 23. Fetal Sex Identification in Maternal Plasma Using Dhort Tandem Repeats on Chromosome X: Gennaro Vecchione
Michela Tomaiuolo
Michelina Sarno
Donatella Colaizzo
Rosella Petraroli
Maria Matteo
Pantaleo Greco
Elvira Grandone
and Maurizio Margaglione. 24. A New Y-chromosome Marker for Noninvasive Fetal Gender Determination: Olga B. Vainer
Aleksey V. Katokhin
Sergey M. Kustov
Valentin V. Vlassov
and Pavel P. Laktionov. Part IV. Circulating Nucleic Acids and Cancer:. 25. DNA Integrity in Plasma and Serum of Patients with Malignant and Benign Diseases: Stefan Holdenrieder
Alexander Burges
Oliver Reich
Fritz W. Spelsberg
and Petra Stieber. 26. Quantification of LINE1 in Circulating DNA as a Molecular Biomarker of Breast Cancer: Eiji Sunami
Anh-Thu Vu
Sandy L. Nguyen
Armando E Giuliano
and Dave S. B. Hoo. 27. Effect of Adjuvant Chemotherapy on Integrity of Free Serum DNA in Patients with Breast Cancer: Ugur Deligezer
Yesim Eralp
Elif Z. Akisik
Ebru E. Akisik
Pinar Saip
Erkan Topuz
and Nejat Dalay. 28. Clinical Relevance of Circulating Nucleosomes in Cancer Disease: Stefan Holdenrieder
Dorothea Nagel
Andreas Schalhorn
Volker Heinemann
Ralf Wilkowski
Joachim von Pawel
Hannelore Raith
Knut Feldmann
Andreas E Kremer
Susanne Müller
Sandra Geiger
Gerhard F Hamann
Dietrich Seidel
and Petra Stieber. 29. Detection and Monitoring of Cell-Free DNA in Blood of Patients with Colorectal Cancer: Heidi Schwarzenbach
Jan Stoehlmacher
Klaus Pantel
and Eray Goekkurt. 30. Detection of Mutated K-ras DNA in Urine
Plasma and Serum from Patients with Colorectal Carcinoma or Adenomatous Polyps: Ying-Hsiu Su
Mengjun Wang
Dean E. Brenner
Pamela A. Norton
and Timothy M. Block. 31. Integrity of Cell-free Plasma DNA in Patients with Lung Cancer and Non-malignant Lung Disease: Bernd Schmidt
Sabine Weickmann
Christian Witt
and Michael Fleischhacker. 32. Cell-surface-bound Circulating DNA as A Prognostic Factor of Lung Cancer: Svetlana N. Tamkovich
Nikolai V. Litviakov
Olga E. Bryzgunova
Aleksey Yu. Dobrodeev
Elena Yu. Rykova
Sergey A. Tuzikov
Aleksandr A. Zav'ialov
Valentin V. Vlassov
Nadezhda V. Cherdyntseva
and Pavel P. Laktionov. 33. Deoxyribonuclease Activity and Circulating DNA Concentration in Blood Plasma of Prostate Tumor Patients: Anna V. Cherepanova
Svetlana N. Tamkovich
Olga E. Bryzgunova
Valentin V. Vlassov
and Pavel P. Laktionov. 34. Methylation-specific Sequencing of GSTP1 Gene Promoter in Circulating/Extracellular DNA from Blood and Urine of Healthy Donors and Prostate Cancer Patients: Olga E. Bryzgunova
Evgeniy S. Morozkin
Sergey V. Yarmoschuk
Valentin V. Vlassov
and Pavel P. Laktionov. 35. Circulating DNA in the Blood of Gastric Cancer Patients: Elena V. Kolesnikova
Svetlana N. Tamkovicha
Olga E. Bryzgunova
Petr I. Shelestyuk
Valentina I. Permyakova
Aleksandr S. Tuzikovd
Valentin V. Vlassov
Pavel P. Laktionov
and Elena Y. Rykova. 36. Methylation-based Analysis of Circulating DNA for Breast Tumors Screening: Elena Y. Rykova
Galina A. Tsvetovskaya
Galina I. Sergeeva
Valentin V. Vlassov
and Pavel P. Laktionov. Part V. Circulating Nucleic Acids and Other Diseases:. 37. Overview of Circulating Nucleic Acids in Plasma/Serum: Update on Potential Prognostic and Diagnostic Value in Pathology Excluding Fetal Medicine and Oncology: Asif N. Butt and R. Swaminathan. 38. Effect of Hypoxia on Circulating Levels of Retina Specific Messenger RNA in Type 2 Diabetes Mellitus: Amy Wong
Simon Merritt
Asif N. Butt
AdrianWilliams
and R. Swaminathan. 39. Retinal Specific mRNA in the Assessment of Diabetic Retinopathy: Z. Shalchi
H. S. Sandhu
A.N. Butt
S. Smith
J. Powrie
and R. Swaminathan. 40. Measurement of circulating Neuron Specific Enolase mRNA in Diabetes Mellitus: H. S. Sandhu
A.N. Butt
J. Powrie
and R. Swaminathan. 41. Hepatitis B Virus X-DNA: A Serum Marker for Early Detection of Resistance Development during Lamivudine Therapy: Wei Zhang
Yan-Hong Li
Shao-Jun Zhu
Yan Zhang
Li Gong
Shu-Mei Wang
Hans Jörg Hacker
Claus Hobe Schröder
Dong-Sheng Cheng
and Ying-Ming Feng. 42. Cell - free DNA of Patients with Cardiomyopathy and rDNA Alone Change the Frequency of Contraction of the Electrically Paced Neonatal Rat Ventricular Myocytes in Culture: N. Bulicheva
O. Fidelina
N. Mkrtumova
M. Neverova
A. Bogush
M. Bogush
O. Roginko
and N. Veiko. 43. Influence of Plasma DNA on Acid-base Balance
Blood Gas Measurement
and Oxygen Transport in Health and Stroke: Irina L. Konorova
Natalya N. Veiko
and Viktor E. Novikov. 44. Circulating 11ß-Hydroxysteroid Dehydrogenase Type 1 mRNA and Cardiovascular Risk Factors: Maise Al Bakir
Asif Butt
and R. Swaminathan. 45. Hypertension and circulating mRNA for 11ß-Hydroxysteroid Dehydrogenase Type II: S. Agalou
A. Butt
Phil Chowienczyk
and R. Swaminathan. 46. Cell-free Plasma DNA during Peritoneal Dialysis
Hemodialysis
and in Patients with Chronic Kidney Disease: Marie Korabecna
Sylvie Opatrna
Jan Wirth
Kamila Rulcova
Jan Eiselt
Frantisek Sefrna
and Ales Horinek. 47. Arrayed Primer EXtension (APEX) for the Non-Invasive Prenatal Diagnosis of ß-thalassaemia Based on Detection of Single Nucleotide Polymorphisms: Thessalia Papasavva
Ioannis Kalikas
Andreanni Kyrri
and Marina Kleanthous. 48. The Housekeeping Gene (ga3pdh) and the Long Interspersed Nuclear Element (line) in the Blood and Organs of the Rats Treated with Cocaine: Anatoliy M. Voskresenskiy and Lena S. Sun. 49. Extracellular Functional Non-Coding Nucleic Acid Bioaptamers and Angiotropin RNP Ribokines in Vascularization and Self-Tolerance: 3D-Episcripts on Domains Shared in Regulator Proteins of the Vascular and Cancer Epigenome: Josef H. Wissler
Joerg E. Wissler
and Enno Logemann. Index of Contributors
Philippe Anker
and Maurice Stroun. 2. Circulating DNA: Its Origin and Fluctuation: Maniesh van der Vaart and Piet J. Pretorius. 3. The Origin of Elevated Levels of Circulating DNA in Blood Plasma of Premature Newborns: N. O. Tuaeva
Z.I. Abramova and V. V. Sofronov. 4. The Effect of Protein Transport Inhibitors on the Production of Extracellular DNA: Evgeniy S. Morozkin
Tatyana I. Babochkina
Valentin V. Vlassov
and Pavel P. Laktionov. 5. Binding and Penetration of Methylated DNA into Primary and Transformed Human Cells: Tatyana E. Skvortsova
Valentin V. Vlassov
and Pavel P. Laktionov. 6. Extracellular DNA Fragments: Factors of Stress Signalling between X-irradiated and Non-irradiated Human Lymphocytes: Aleksei V. Ermakov
Svetlana V. Kostyuk
Marina S. Konkova
Natalya A. Egolina
Elena M. Malinovskaya
and Natalya N. Veiko. 7. Isolation and Sequencing of Short Cell-Surface-Bound DNA: Vera S. Mal'shakova
Dmitry V. Pyshnyi
Alexander A. Bondar
Valentin V. Vlassov
and Pavel P. Laktionov. 8. Extracellular RNA Spontaneously Internalized by Human Cells Undergo Deamination of Adenosines: Elena V. Kuligina
Oksana V. Vratskih
Dmitry V. Semenov
Vera A. Matveea
and Vladimir A. Richter. 9. Circulating Nucleic Acids in the Assessment of Endogenous Growth Hormone Production: H. Thakkar
A.N. Butt
J. Powrie
R. Holt
and R. Swaminathan. 10. The Involvement of Different Mobile Line Copies of Blood Plasma and Extrachromosomal DNA of Liver Cells in Systemic Adaptive Response: Sophiya S. Sherlina and Viktor G. Vladimirov. Part II. Methodology:. 11. Transrenal Nucleic Acids from Proof-of-Principle to Clinical Tests: Problems and Solutions: Hovsep S. Melkonyan
W. John Feaver
Erik Meyer
Vladimir Scheinker
Eugene M. Shekhtman
Zhenghan Xin
and Samuil R. Umansky. 12. Removal of High Molecular Weight DNA by Carboxylated Magnetic Beads Enhances the Detection of Mutated K-ras DNA in Urine: Ying-Hsiu Su
Janet Song
Zhili Wang
Xiao-He Wang
Mengjun Wang
Dean E. Brenner
and Timothy M. Block. 13. A Method for Characterization of Total Circulating DNA: Maniesh van der Vaart and Piet J. Pretorius. 14. Isolation and Extraction of Circulating Tumour DNA from Patients with Small Cell Lung Cancer: Ruth E Board
Victoria S Williams
Lucy Knight
Jacqueline Shaw
Alastair Greystoke
Malcolm Ranson
Caroline Dive
Fiona H Blackhall
and Andrew Hughes. 15. Stability of ß-Actin mRNA in Plasma: N.C. Holford
H.S. Sandhu
H. Thakkar
A.N. Butt
and R. Swaminathan. 16. Normalization of Circulating Nucleic Acid Results. Should We Use ß-Actin?: N.C. Holford
A. Ramoutar
A.N. Butt
and R. Swaminathan. 17. Artificial BOX C/D RNA Targeted to Branch Point Adenosine Impairs Splicing by Exon Exclusion: Dmitry V. Semenov
Oksana V. Vratskih
Elena V. Kuligina
and Vladimir A. Richter. 18. Optimization of Purification of Human Cell-free mRNA from Plasma: Tadeja Dovc-Drnovsek
Barbara Emersic
Primoz Rozman
Darko Cerne
and Jana Lukac-Bajalo. 19. Fragments of Non-coding RNA in Plasma of Human Blood: Dmitry V. Semenov
Dmitry N. Baryakin
Tatyana P. Kamynina
Elena V. Kuligina
and Vladimir A. Richter. 20. An Improved Method for the Isolation of Free-circulating Plasma DNA and Cell-free DNA from Other Body Fluids: Christoph Kirsch
Sabine Weickmann
Bernd Schmidt
and Michael Fleischhacker. Part III. Fetal Nucleic Acids:. 21. Fetal Nucleic Acids in Maternal Plasma: Towards the Development of Noninvasive Prenatal Diagnosis of Fetal Chromosomal Aneuploidies: Y.M. Dennis Lo. 22. Phenotype and mRNA Expression of Syncytiotrophoblast Microparticles Isolated from Human Placenta: Belinda Kumpel
May-Jean King
Suren Sooranna
Dave Jackson
Jane Eastlake
Rong Cheng
and Mark Johnson. 23. Fetal Sex Identification in Maternal Plasma Using Dhort Tandem Repeats on Chromosome X: Gennaro Vecchione
Michela Tomaiuolo
Michelina Sarno
Donatella Colaizzo
Rosella Petraroli
Maria Matteo
Pantaleo Greco
Elvira Grandone
and Maurizio Margaglione. 24. A New Y-chromosome Marker for Noninvasive Fetal Gender Determination: Olga B. Vainer
Aleksey V. Katokhin
Sergey M. Kustov
Valentin V. Vlassov
and Pavel P. Laktionov. Part IV. Circulating Nucleic Acids and Cancer:. 25. DNA Integrity in Plasma and Serum of Patients with Malignant and Benign Diseases: Stefan Holdenrieder
Alexander Burges
Oliver Reich
Fritz W. Spelsberg
and Petra Stieber. 26. Quantification of LINE1 in Circulating DNA as a Molecular Biomarker of Breast Cancer: Eiji Sunami
Anh-Thu Vu
Sandy L. Nguyen
Armando E Giuliano
and Dave S. B. Hoo. 27. Effect of Adjuvant Chemotherapy on Integrity of Free Serum DNA in Patients with Breast Cancer: Ugur Deligezer
Yesim Eralp
Elif Z. Akisik
Ebru E. Akisik
Pinar Saip
Erkan Topuz
and Nejat Dalay. 28. Clinical Relevance of Circulating Nucleosomes in Cancer Disease: Stefan Holdenrieder
Dorothea Nagel
Andreas Schalhorn
Volker Heinemann
Ralf Wilkowski
Joachim von Pawel
Hannelore Raith
Knut Feldmann
Andreas E Kremer
Susanne Müller
Sandra Geiger
Gerhard F Hamann
Dietrich Seidel
and Petra Stieber. 29. Detection and Monitoring of Cell-Free DNA in Blood of Patients with Colorectal Cancer: Heidi Schwarzenbach
Jan Stoehlmacher
Klaus Pantel
and Eray Goekkurt. 30. Detection of Mutated K-ras DNA in Urine
Plasma and Serum from Patients with Colorectal Carcinoma or Adenomatous Polyps: Ying-Hsiu Su
Mengjun Wang
Dean E. Brenner
Pamela A. Norton
and Timothy M. Block. 31. Integrity of Cell-free Plasma DNA in Patients with Lung Cancer and Non-malignant Lung Disease: Bernd Schmidt
Sabine Weickmann
Christian Witt
and Michael Fleischhacker. 32. Cell-surface-bound Circulating DNA as A Prognostic Factor of Lung Cancer: Svetlana N. Tamkovich
Nikolai V. Litviakov
Olga E. Bryzgunova
Aleksey Yu. Dobrodeev
Elena Yu. Rykova
Sergey A. Tuzikov
Aleksandr A. Zav'ialov
Valentin V. Vlassov
Nadezhda V. Cherdyntseva
and Pavel P. Laktionov. 33. Deoxyribonuclease Activity and Circulating DNA Concentration in Blood Plasma of Prostate Tumor Patients: Anna V. Cherepanova
Svetlana N. Tamkovich
Olga E. Bryzgunova
Valentin V. Vlassov
and Pavel P. Laktionov. 34. Methylation-specific Sequencing of GSTP1 Gene Promoter in Circulating/Extracellular DNA from Blood and Urine of Healthy Donors and Prostate Cancer Patients: Olga E. Bryzgunova
Evgeniy S. Morozkin
Sergey V. Yarmoschuk
Valentin V. Vlassov
and Pavel P. Laktionov. 35. Circulating DNA in the Blood of Gastric Cancer Patients: Elena V. Kolesnikova
Svetlana N. Tamkovicha
Olga E. Bryzgunova
Petr I. Shelestyuk
Valentina I. Permyakova
Aleksandr S. Tuzikovd
Valentin V. Vlassov
Pavel P. Laktionov
and Elena Y. Rykova. 36. Methylation-based Analysis of Circulating DNA for Breast Tumors Screening: Elena Y. Rykova
Galina A. Tsvetovskaya
Galina I. Sergeeva
Valentin V. Vlassov
and Pavel P. Laktionov. Part V. Circulating Nucleic Acids and Other Diseases:. 37. Overview of Circulating Nucleic Acids in Plasma/Serum: Update on Potential Prognostic and Diagnostic Value in Pathology Excluding Fetal Medicine and Oncology: Asif N. Butt and R. Swaminathan. 38. Effect of Hypoxia on Circulating Levels of Retina Specific Messenger RNA in Type 2 Diabetes Mellitus: Amy Wong
Simon Merritt
Asif N. Butt
AdrianWilliams
and R. Swaminathan. 39. Retinal Specific mRNA in the Assessment of Diabetic Retinopathy: Z. Shalchi
H. S. Sandhu
A.N. Butt
S. Smith
J. Powrie
and R. Swaminathan. 40. Measurement of circulating Neuron Specific Enolase mRNA in Diabetes Mellitus: H. S. Sandhu
A.N. Butt
J. Powrie
and R. Swaminathan. 41. Hepatitis B Virus X-DNA: A Serum Marker for Early Detection of Resistance Development during Lamivudine Therapy: Wei Zhang
Yan-Hong Li
Shao-Jun Zhu
Yan Zhang
Li Gong
Shu-Mei Wang
Hans Jörg Hacker
Claus Hobe Schröder
Dong-Sheng Cheng
and Ying-Ming Feng. 42. Cell - free DNA of Patients with Cardiomyopathy and rDNA Alone Change the Frequency of Contraction of the Electrically Paced Neonatal Rat Ventricular Myocytes in Culture: N. Bulicheva
O. Fidelina
N. Mkrtumova
M. Neverova
A. Bogush
M. Bogush
O. Roginko
and N. Veiko. 43. Influence of Plasma DNA on Acid-base Balance
Blood Gas Measurement
and Oxygen Transport in Health and Stroke: Irina L. Konorova
Natalya N. Veiko
and Viktor E. Novikov. 44. Circulating 11ß-Hydroxysteroid Dehydrogenase Type 1 mRNA and Cardiovascular Risk Factors: Maise Al Bakir
Asif Butt
and R. Swaminathan. 45. Hypertension and circulating mRNA for 11ß-Hydroxysteroid Dehydrogenase Type II: S. Agalou
A. Butt
Phil Chowienczyk
and R. Swaminathan. 46. Cell-free Plasma DNA during Peritoneal Dialysis
Hemodialysis
and in Patients with Chronic Kidney Disease: Marie Korabecna
Sylvie Opatrna
Jan Wirth
Kamila Rulcova
Jan Eiselt
Frantisek Sefrna
and Ales Horinek. 47. Arrayed Primer EXtension (APEX) for the Non-Invasive Prenatal Diagnosis of ß-thalassaemia Based on Detection of Single Nucleotide Polymorphisms: Thessalia Papasavva
Ioannis Kalikas
Andreanni Kyrri
and Marina Kleanthous. 48. The Housekeeping Gene (ga3pdh) and the Long Interspersed Nuclear Element (line) in the Blood and Organs of the Rats Treated with Cocaine: Anatoliy M. Voskresenskiy and Lena S. Sun. 49. Extracellular Functional Non-Coding Nucleic Acid Bioaptamers and Angiotropin RNP Ribokines in Vascularization and Self-Tolerance: 3D-Episcripts on Domains Shared in Regulator Proteins of the Vascular and Cancer Epigenome: Josef H. Wissler
Joerg E. Wissler
and Enno Logemann. Index of Contributors
Preface: Peter B. Gahan and R. Swaminathan. Circulating Nucleic Acids in Plasma and Serum: Recent Developments: Peter B. Gahan and R. Swaminathan. Part I. Basic Research:. 1. Metabolic DNA as the Origin of Spontaneously Released DNA?: Peter Gahan
Philippe Anker
and Maurice Stroun. 2. Circulating DNA: Its Origin and Fluctuation: Maniesh van der Vaart and Piet J. Pretorius. 3. The Origin of Elevated Levels of Circulating DNA in Blood Plasma of Premature Newborns: N. O. Tuaeva
Z.I. Abramova and V. V. Sofronov. 4. The Effect of Protein Transport Inhibitors on the Production of Extracellular DNA: Evgeniy S. Morozkin
Tatyana I. Babochkina
Valentin V. Vlassov
and Pavel P. Laktionov. 5. Binding and Penetration of Methylated DNA into Primary and Transformed Human Cells: Tatyana E. Skvortsova
Valentin V. Vlassov
and Pavel P. Laktionov. 6. Extracellular DNA Fragments: Factors of Stress Signalling between X-irradiated and Non-irradiated Human Lymphocytes: Aleksei V. Ermakov
Svetlana V. Kostyuk
Marina S. Konkova
Natalya A. Egolina
Elena M. Malinovskaya
and Natalya N. Veiko. 7. Isolation and Sequencing of Short Cell-Surface-Bound DNA: Vera S. Mal'shakova
Dmitry V. Pyshnyi
Alexander A. Bondar
Valentin V. Vlassov
and Pavel P. Laktionov. 8. Extracellular RNA Spontaneously Internalized by Human Cells Undergo Deamination of Adenosines: Elena V. Kuligina
Oksana V. Vratskih
Dmitry V. Semenov
Vera A. Matveea
and Vladimir A. Richter. 9. Circulating Nucleic Acids in the Assessment of Endogenous Growth Hormone Production: H. Thakkar
A.N. Butt
J. Powrie
R. Holt
and R. Swaminathan. 10. The Involvement of Different Mobile Line Copies of Blood Plasma and Extrachromosomal DNA of Liver Cells in Systemic Adaptive Response: Sophiya S. Sherlina and Viktor G. Vladimirov. Part II. Methodology:. 11. Transrenal Nucleic Acids from Proof-of-Principle to Clinical Tests: Problems and Solutions: Hovsep S. Melkonyan
W. John Feaver
Erik Meyer
Vladimir Scheinker
Eugene M. Shekhtman
Zhenghan Xin
and Samuil R. Umansky. 12. Removal of High Molecular Weight DNA by Carboxylated Magnetic Beads Enhances the Detection of Mutated K-ras DNA in Urine: Ying-Hsiu Su
Janet Song
Zhili Wang
Xiao-He Wang
Mengjun Wang
Dean E. Brenner
and Timothy M. Block. 13. A Method for Characterization of Total Circulating DNA: Maniesh van der Vaart and Piet J. Pretorius. 14. Isolation and Extraction of Circulating Tumour DNA from Patients with Small Cell Lung Cancer: Ruth E Board
Victoria S Williams
Lucy Knight
Jacqueline Shaw
Alastair Greystoke
Malcolm Ranson
Caroline Dive
Fiona H Blackhall
and Andrew Hughes. 15. Stability of ß-Actin mRNA in Plasma: N.C. Holford
H.S. Sandhu
H. Thakkar
A.N. Butt
and R. Swaminathan. 16. Normalization of Circulating Nucleic Acid Results. Should We Use ß-Actin?: N.C. Holford
A. Ramoutar
A.N. Butt
and R. Swaminathan. 17. Artificial BOX C/D RNA Targeted to Branch Point Adenosine Impairs Splicing by Exon Exclusion: Dmitry V. Semenov
Oksana V. Vratskih
Elena V. Kuligina
and Vladimir A. Richter. 18. Optimization of Purification of Human Cell-free mRNA from Plasma: Tadeja Dovc-Drnovsek
Barbara Emersic
Primoz Rozman
Darko Cerne
and Jana Lukac-Bajalo. 19. Fragments of Non-coding RNA in Plasma of Human Blood: Dmitry V. Semenov
Dmitry N. Baryakin
Tatyana P. Kamynina
Elena V. Kuligina
and Vladimir A. Richter. 20. An Improved Method for the Isolation of Free-circulating Plasma DNA and Cell-free DNA from Other Body Fluids: Christoph Kirsch
Sabine Weickmann
Bernd Schmidt
and Michael Fleischhacker. Part III. Fetal Nucleic Acids:. 21. Fetal Nucleic Acids in Maternal Plasma: Towards the Development of Noninvasive Prenatal Diagnosis of Fetal Chromosomal Aneuploidies: Y.M. Dennis Lo. 22. Phenotype and mRNA Expression of Syncytiotrophoblast Microparticles Isolated from Human Placenta: Belinda Kumpel
May-Jean King
Suren Sooranna
Dave Jackson
Jane Eastlake
Rong Cheng
and Mark Johnson. 23. Fetal Sex Identification in Maternal Plasma Using Dhort Tandem Repeats on Chromosome X: Gennaro Vecchione
Michela Tomaiuolo
Michelina Sarno
Donatella Colaizzo
Rosella Petraroli
Maria Matteo
Pantaleo Greco
Elvira Grandone
and Maurizio Margaglione. 24. A New Y-chromosome Marker for Noninvasive Fetal Gender Determination: Olga B. Vainer
Aleksey V. Katokhin
Sergey M. Kustov
Valentin V. Vlassov
and Pavel P. Laktionov. Part IV. Circulating Nucleic Acids and Cancer:. 25. DNA Integrity in Plasma and Serum of Patients with Malignant and Benign Diseases: Stefan Holdenrieder
Alexander Burges
Oliver Reich
Fritz W. Spelsberg
and Petra Stieber. 26. Quantification of LINE1 in Circulating DNA as a Molecular Biomarker of Breast Cancer: Eiji Sunami
Anh-Thu Vu
Sandy L. Nguyen
Armando E Giuliano
and Dave S. B. Hoo. 27. Effect of Adjuvant Chemotherapy on Integrity of Free Serum DNA in Patients with Breast Cancer: Ugur Deligezer
Yesim Eralp
Elif Z. Akisik
Ebru E. Akisik
Pinar Saip
Erkan Topuz
and Nejat Dalay. 28. Clinical Relevance of Circulating Nucleosomes in Cancer Disease: Stefan Holdenrieder
Dorothea Nagel
Andreas Schalhorn
Volker Heinemann
Ralf Wilkowski
Joachim von Pawel
Hannelore Raith
Knut Feldmann
Andreas E Kremer
Susanne Müller
Sandra Geiger
Gerhard F Hamann
Dietrich Seidel
and Petra Stieber. 29. Detection and Monitoring of Cell-Free DNA in Blood of Patients with Colorectal Cancer: Heidi Schwarzenbach
Jan Stoehlmacher
Klaus Pantel
and Eray Goekkurt. 30. Detection of Mutated K-ras DNA in Urine
Plasma and Serum from Patients with Colorectal Carcinoma or Adenomatous Polyps: Ying-Hsiu Su
Mengjun Wang
Dean E. Brenner
Pamela A. Norton
and Timothy M. Block. 31. Integrity of Cell-free Plasma DNA in Patients with Lung Cancer and Non-malignant Lung Disease: Bernd Schmidt
Sabine Weickmann
Christian Witt
and Michael Fleischhacker. 32. Cell-surface-bound Circulating DNA as A Prognostic Factor of Lung Cancer: Svetlana N. Tamkovich
Nikolai V. Litviakov
Olga E. Bryzgunova
Aleksey Yu. Dobrodeev
Elena Yu. Rykova
Sergey A. Tuzikov
Aleksandr A. Zav'ialov
Valentin V. Vlassov
Nadezhda V. Cherdyntseva
and Pavel P. Laktionov. 33. Deoxyribonuclease Activity and Circulating DNA Concentration in Blood Plasma of Prostate Tumor Patients: Anna V. Cherepanova
Svetlana N. Tamkovich
Olga E. Bryzgunova
Valentin V. Vlassov
and Pavel P. Laktionov. 34. Methylation-specific Sequencing of GSTP1 Gene Promoter in Circulating/Extracellular DNA from Blood and Urine of Healthy Donors and Prostate Cancer Patients: Olga E. Bryzgunova
Evgeniy S. Morozkin
Sergey V. Yarmoschuk
Valentin V. Vlassov
and Pavel P. Laktionov. 35. Circulating DNA in the Blood of Gastric Cancer Patients: Elena V. Kolesnikova
Svetlana N. Tamkovicha
Olga E. Bryzgunova
Petr I. Shelestyuk
Valentina I. Permyakova
Aleksandr S. Tuzikovd
Valentin V. Vlassov
Pavel P. Laktionov
and Elena Y. Rykova. 36. Methylation-based Analysis of Circulating DNA for Breast Tumors Screening: Elena Y. Rykova
Galina A. Tsvetovskaya
Galina I. Sergeeva
Valentin V. Vlassov
and Pavel P. Laktionov. Part V. Circulating Nucleic Acids and Other Diseases:. 37. Overview of Circulating Nucleic Acids in Plasma/Serum: Update on Potential Prognostic and Diagnostic Value in Pathology Excluding Fetal Medicine and Oncology: Asif N. Butt and R. Swaminathan. 38. Effect of Hypoxia on Circulating Levels of Retina Specific Messenger RNA in Type 2 Diabetes Mellitus: Amy Wong
Simon Merritt
Asif N. Butt
AdrianWilliams
and R. Swaminathan. 39. Retinal Specific mRNA in the Assessment of Diabetic Retinopathy: Z. Shalchi
H. S. Sandhu
A.N. Butt
S. Smith
J. Powrie
and R. Swaminathan. 40. Measurement of circulating Neuron Specific Enolase mRNA in Diabetes Mellitus: H. S. Sandhu
A.N. Butt
J. Powrie
and R. Swaminathan. 41. Hepatitis B Virus X-DNA: A Serum Marker for Early Detection of Resistance Development during Lamivudine Therapy: Wei Zhang
Yan-Hong Li
Shao-Jun Zhu
Yan Zhang
Li Gong
Shu-Mei Wang
Hans Jörg Hacker
Claus Hobe Schröder
Dong-Sheng Cheng
and Ying-Ming Feng. 42. Cell - free DNA of Patients with Cardiomyopathy and rDNA Alone Change the Frequency of Contraction of the Electrically Paced Neonatal Rat Ventricular Myocytes in Culture: N. Bulicheva
O. Fidelina
N. Mkrtumova
M. Neverova
A. Bogush
M. Bogush
O. Roginko
and N. Veiko. 43. Influence of Plasma DNA on Acid-base Balance
Blood Gas Measurement
and Oxygen Transport in Health and Stroke: Irina L. Konorova
Natalya N. Veiko
and Viktor E. Novikov. 44. Circulating 11ß-Hydroxysteroid Dehydrogenase Type 1 mRNA and Cardiovascular Risk Factors: Maise Al Bakir
Asif Butt
and R. Swaminathan. 45. Hypertension and circulating mRNA for 11ß-Hydroxysteroid Dehydrogenase Type II: S. Agalou
A. Butt
Phil Chowienczyk
and R. Swaminathan. 46. Cell-free Plasma DNA during Peritoneal Dialysis
Hemodialysis
and in Patients with Chronic Kidney Disease: Marie Korabecna
Sylvie Opatrna
Jan Wirth
Kamila Rulcova
Jan Eiselt
Frantisek Sefrna
and Ales Horinek. 47. Arrayed Primer EXtension (APEX) for the Non-Invasive Prenatal Diagnosis of ß-thalassaemia Based on Detection of Single Nucleotide Polymorphisms: Thessalia Papasavva
Ioannis Kalikas
Andreanni Kyrri
and Marina Kleanthous. 48. The Housekeeping Gene (ga3pdh) and the Long Interspersed Nuclear Element (line) in the Blood and Organs of the Rats Treated with Cocaine: Anatoliy M. Voskresenskiy and Lena S. Sun. 49. Extracellular Functional Non-Coding Nucleic Acid Bioaptamers and Angiotropin RNP Ribokines in Vascularization and Self-Tolerance: 3D-Episcripts on Domains Shared in Regulator Proteins of the Vascular and Cancer Epigenome: Josef H. Wissler
Joerg E. Wissler
and Enno Logemann. Index of Contributors
Philippe Anker
and Maurice Stroun. 2. Circulating DNA: Its Origin and Fluctuation: Maniesh van der Vaart and Piet J. Pretorius. 3. The Origin of Elevated Levels of Circulating DNA in Blood Plasma of Premature Newborns: N. O. Tuaeva
Z.I. Abramova and V. V. Sofronov. 4. The Effect of Protein Transport Inhibitors on the Production of Extracellular DNA: Evgeniy S. Morozkin
Tatyana I. Babochkina
Valentin V. Vlassov
and Pavel P. Laktionov. 5. Binding and Penetration of Methylated DNA into Primary and Transformed Human Cells: Tatyana E. Skvortsova
Valentin V. Vlassov
and Pavel P. Laktionov. 6. Extracellular DNA Fragments: Factors of Stress Signalling between X-irradiated and Non-irradiated Human Lymphocytes: Aleksei V. Ermakov
Svetlana V. Kostyuk
Marina S. Konkova
Natalya A. Egolina
Elena M. Malinovskaya
and Natalya N. Veiko. 7. Isolation and Sequencing of Short Cell-Surface-Bound DNA: Vera S. Mal'shakova
Dmitry V. Pyshnyi
Alexander A. Bondar
Valentin V. Vlassov
and Pavel P. Laktionov. 8. Extracellular RNA Spontaneously Internalized by Human Cells Undergo Deamination of Adenosines: Elena V. Kuligina
Oksana V. Vratskih
Dmitry V. Semenov
Vera A. Matveea
and Vladimir A. Richter. 9. Circulating Nucleic Acids in the Assessment of Endogenous Growth Hormone Production: H. Thakkar
A.N. Butt
J. Powrie
R. Holt
and R. Swaminathan. 10. The Involvement of Different Mobile Line Copies of Blood Plasma and Extrachromosomal DNA of Liver Cells in Systemic Adaptive Response: Sophiya S. Sherlina and Viktor G. Vladimirov. Part II. Methodology:. 11. Transrenal Nucleic Acids from Proof-of-Principle to Clinical Tests: Problems and Solutions: Hovsep S. Melkonyan
W. John Feaver
Erik Meyer
Vladimir Scheinker
Eugene M. Shekhtman
Zhenghan Xin
and Samuil R. Umansky. 12. Removal of High Molecular Weight DNA by Carboxylated Magnetic Beads Enhances the Detection of Mutated K-ras DNA in Urine: Ying-Hsiu Su
Janet Song
Zhili Wang
Xiao-He Wang
Mengjun Wang
Dean E. Brenner
and Timothy M. Block. 13. A Method for Characterization of Total Circulating DNA: Maniesh van der Vaart and Piet J. Pretorius. 14. Isolation and Extraction of Circulating Tumour DNA from Patients with Small Cell Lung Cancer: Ruth E Board
Victoria S Williams
Lucy Knight
Jacqueline Shaw
Alastair Greystoke
Malcolm Ranson
Caroline Dive
Fiona H Blackhall
and Andrew Hughes. 15. Stability of ß-Actin mRNA in Plasma: N.C. Holford
H.S. Sandhu
H. Thakkar
A.N. Butt
and R. Swaminathan. 16. Normalization of Circulating Nucleic Acid Results. Should We Use ß-Actin?: N.C. Holford
A. Ramoutar
A.N. Butt
and R. Swaminathan. 17. Artificial BOX C/D RNA Targeted to Branch Point Adenosine Impairs Splicing by Exon Exclusion: Dmitry V. Semenov
Oksana V. Vratskih
Elena V. Kuligina
and Vladimir A. Richter. 18. Optimization of Purification of Human Cell-free mRNA from Plasma: Tadeja Dovc-Drnovsek
Barbara Emersic
Primoz Rozman
Darko Cerne
and Jana Lukac-Bajalo. 19. Fragments of Non-coding RNA in Plasma of Human Blood: Dmitry V. Semenov
Dmitry N. Baryakin
Tatyana P. Kamynina
Elena V. Kuligina
and Vladimir A. Richter. 20. An Improved Method for the Isolation of Free-circulating Plasma DNA and Cell-free DNA from Other Body Fluids: Christoph Kirsch
Sabine Weickmann
Bernd Schmidt
and Michael Fleischhacker. Part III. Fetal Nucleic Acids:. 21. Fetal Nucleic Acids in Maternal Plasma: Towards the Development of Noninvasive Prenatal Diagnosis of Fetal Chromosomal Aneuploidies: Y.M. Dennis Lo. 22. Phenotype and mRNA Expression of Syncytiotrophoblast Microparticles Isolated from Human Placenta: Belinda Kumpel
May-Jean King
Suren Sooranna
Dave Jackson
Jane Eastlake
Rong Cheng
and Mark Johnson. 23. Fetal Sex Identification in Maternal Plasma Using Dhort Tandem Repeats on Chromosome X: Gennaro Vecchione
Michela Tomaiuolo
Michelina Sarno
Donatella Colaizzo
Rosella Petraroli
Maria Matteo
Pantaleo Greco
Elvira Grandone
and Maurizio Margaglione. 24. A New Y-chromosome Marker for Noninvasive Fetal Gender Determination: Olga B. Vainer
Aleksey V. Katokhin
Sergey M. Kustov
Valentin V. Vlassov
and Pavel P. Laktionov. Part IV. Circulating Nucleic Acids and Cancer:. 25. DNA Integrity in Plasma and Serum of Patients with Malignant and Benign Diseases: Stefan Holdenrieder
Alexander Burges
Oliver Reich
Fritz W. Spelsberg
and Petra Stieber. 26. Quantification of LINE1 in Circulating DNA as a Molecular Biomarker of Breast Cancer: Eiji Sunami
Anh-Thu Vu
Sandy L. Nguyen
Armando E Giuliano
and Dave S. B. Hoo. 27. Effect of Adjuvant Chemotherapy on Integrity of Free Serum DNA in Patients with Breast Cancer: Ugur Deligezer
Yesim Eralp
Elif Z. Akisik
Ebru E. Akisik
Pinar Saip
Erkan Topuz
and Nejat Dalay. 28. Clinical Relevance of Circulating Nucleosomes in Cancer Disease: Stefan Holdenrieder
Dorothea Nagel
Andreas Schalhorn
Volker Heinemann
Ralf Wilkowski
Joachim von Pawel
Hannelore Raith
Knut Feldmann
Andreas E Kremer
Susanne Müller
Sandra Geiger
Gerhard F Hamann
Dietrich Seidel
and Petra Stieber. 29. Detection and Monitoring of Cell-Free DNA in Blood of Patients with Colorectal Cancer: Heidi Schwarzenbach
Jan Stoehlmacher
Klaus Pantel
and Eray Goekkurt. 30. Detection of Mutated K-ras DNA in Urine
Plasma and Serum from Patients with Colorectal Carcinoma or Adenomatous Polyps: Ying-Hsiu Su
Mengjun Wang
Dean E. Brenner
Pamela A. Norton
and Timothy M. Block. 31. Integrity of Cell-free Plasma DNA in Patients with Lung Cancer and Non-malignant Lung Disease: Bernd Schmidt
Sabine Weickmann
Christian Witt
and Michael Fleischhacker. 32. Cell-surface-bound Circulating DNA as A Prognostic Factor of Lung Cancer: Svetlana N. Tamkovich
Nikolai V. Litviakov
Olga E. Bryzgunova
Aleksey Yu. Dobrodeev
Elena Yu. Rykova
Sergey A. Tuzikov
Aleksandr A. Zav'ialov
Valentin V. Vlassov
Nadezhda V. Cherdyntseva
and Pavel P. Laktionov. 33. Deoxyribonuclease Activity and Circulating DNA Concentration in Blood Plasma of Prostate Tumor Patients: Anna V. Cherepanova
Svetlana N. Tamkovich
Olga E. Bryzgunova
Valentin V. Vlassov
and Pavel P. Laktionov. 34. Methylation-specific Sequencing of GSTP1 Gene Promoter in Circulating/Extracellular DNA from Blood and Urine of Healthy Donors and Prostate Cancer Patients: Olga E. Bryzgunova
Evgeniy S. Morozkin
Sergey V. Yarmoschuk
Valentin V. Vlassov
and Pavel P. Laktionov. 35. Circulating DNA in the Blood of Gastric Cancer Patients: Elena V. Kolesnikova
Svetlana N. Tamkovicha
Olga E. Bryzgunova
Petr I. Shelestyuk
Valentina I. Permyakova
Aleksandr S. Tuzikovd
Valentin V. Vlassov
Pavel P. Laktionov
and Elena Y. Rykova. 36. Methylation-based Analysis of Circulating DNA for Breast Tumors Screening: Elena Y. Rykova
Galina A. Tsvetovskaya
Galina I. Sergeeva
Valentin V. Vlassov
and Pavel P. Laktionov. Part V. Circulating Nucleic Acids and Other Diseases:. 37. Overview of Circulating Nucleic Acids in Plasma/Serum: Update on Potential Prognostic and Diagnostic Value in Pathology Excluding Fetal Medicine and Oncology: Asif N. Butt and R. Swaminathan. 38. Effect of Hypoxia on Circulating Levels of Retina Specific Messenger RNA in Type 2 Diabetes Mellitus: Amy Wong
Simon Merritt
Asif N. Butt
AdrianWilliams
and R. Swaminathan. 39. Retinal Specific mRNA in the Assessment of Diabetic Retinopathy: Z. Shalchi
H. S. Sandhu
A.N. Butt
S. Smith
J. Powrie
and R. Swaminathan. 40. Measurement of circulating Neuron Specific Enolase mRNA in Diabetes Mellitus: H. S. Sandhu
A.N. Butt
J. Powrie
and R. Swaminathan. 41. Hepatitis B Virus X-DNA: A Serum Marker for Early Detection of Resistance Development during Lamivudine Therapy: Wei Zhang
Yan-Hong Li
Shao-Jun Zhu
Yan Zhang
Li Gong
Shu-Mei Wang
Hans Jörg Hacker
Claus Hobe Schröder
Dong-Sheng Cheng
and Ying-Ming Feng. 42. Cell - free DNA of Patients with Cardiomyopathy and rDNA Alone Change the Frequency of Contraction of the Electrically Paced Neonatal Rat Ventricular Myocytes in Culture: N. Bulicheva
O. Fidelina
N. Mkrtumova
M. Neverova
A. Bogush
M. Bogush
O. Roginko
and N. Veiko. 43. Influence of Plasma DNA on Acid-base Balance
Blood Gas Measurement
and Oxygen Transport in Health and Stroke: Irina L. Konorova
Natalya N. Veiko
and Viktor E. Novikov. 44. Circulating 11ß-Hydroxysteroid Dehydrogenase Type 1 mRNA and Cardiovascular Risk Factors: Maise Al Bakir
Asif Butt
and R. Swaminathan. 45. Hypertension and circulating mRNA for 11ß-Hydroxysteroid Dehydrogenase Type II: S. Agalou
A. Butt
Phil Chowienczyk
and R. Swaminathan. 46. Cell-free Plasma DNA during Peritoneal Dialysis
Hemodialysis
and in Patients with Chronic Kidney Disease: Marie Korabecna
Sylvie Opatrna
Jan Wirth
Kamila Rulcova
Jan Eiselt
Frantisek Sefrna
and Ales Horinek. 47. Arrayed Primer EXtension (APEX) for the Non-Invasive Prenatal Diagnosis of ß-thalassaemia Based on Detection of Single Nucleotide Polymorphisms: Thessalia Papasavva
Ioannis Kalikas
Andreanni Kyrri
and Marina Kleanthous. 48. The Housekeeping Gene (ga3pdh) and the Long Interspersed Nuclear Element (line) in the Blood and Organs of the Rats Treated with Cocaine: Anatoliy M. Voskresenskiy and Lena S. Sun. 49. Extracellular Functional Non-Coding Nucleic Acid Bioaptamers and Angiotropin RNP Ribokines in Vascularization and Self-Tolerance: 3D-Episcripts on Domains Shared in Regulator Proteins of the Vascular and Cancer Epigenome: Josef H. Wissler
Joerg E. Wissler
and Enno Logemann. Index of Contributors