Klimawandel und Anthropogenisierung sind die Haupttreiber für die Variabilität von Flussläufen. However, understanding of their simultaneous impact on discharges is limited. As a contribution to address this limitation, the objective of this study is to assess the impact of climate change and anthropization on the discharges of two watersheds of Central Africa (Nyong and Ntem) over a recent period. For this, the hydropluviometric data of the watersheds concerned were analyzed using the Pettitt test. Similarly, the dynamics of the main land use modes (LUM) have been assessed, through classifications obtained from the processing of Landsat satellite images of the watersheds studied on two dates. The results of this study show that in Central Africa, annual discharges have decreased significantly since the 1970s, and yet the decline in annual rainfall does not become significant until the 2000s.