Koumtebaye Elysee, Sun Li, Yuan Shengtao

Anti tumor activity of XAP on human gastric cancer cells

• Broschiertes Buch

Produktbeschreibung

Apoptosis induction is an important mechanism in chemotherapy and the deeper understanding of apoptosis regulation in normal and neoplastic cells is a right target for the development of more selective and efficacious therapeutic agents. Xiaoaiping (XAP), extracted from Marsdenia tenacissima (Asclepiadaceae) is a Chinese medicinal plant used traditionally to treat cough and asthma. Our study has demonstrated that XAP can significantly inhibit the proliferation of both cell lines (HCC BEL-7402 and Human gastric cancer SGC-7901) in vitro. Xiaoaiping also showed significant inhibition of human gastric cancer SGC-7901cells transplanted in nude mice. Molecular analysis revealed that XAP arrested the cell cycle progression at S phase and induced apoptosis through caspase activation.

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Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 96
• Erscheinungstermin: 9. September 2019
• Englisch
• Abmessung: 220mm x 150mm x 6mm
• Gewicht: 161g
• ISBN-13: 9786200299123
• ISBN-10: 6200299129
• Artikelnr.: 57868535

Autorenporträt

Koumtebaye Elysee nasceu em 26 de Maio de 1983, em Koumra (província de Mandoul), Chade. É mestre em Farmacologia pela Faculdade de Farmácia da Universidade Farmacêutica da China e bacharel em Ciências Biomédicas e Farmacêuticas pelo Instituto de Pós-Graduação em Ciência e Tecnologia da Abeche (IUSTA), Chade.