Antibacterial Activities of Some New Heterocyclic Compound - Abdul Hussein Alsafee, Bassam;Mohamed Abdulridha, Maitham;Taher Abbas, Ali
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The five member ring as 1,3,4 - thiadiazole and 1,3,4 - Oxadiazole bearing Schiff bases derivatives were prepared in our study by reacting the 1,3,4 - thiadiazole part with 1,3,4 - oxadiazole part in ethanol to produce 1,3,4 - oxadiazole hydrazinyl - 1,3,4 - thiadiazole, which were treated with aromatic aldehyde to produce of 1,3,4 - thiadiazole hydrazinyl 1,3,4 - oxadiazole bearing Schiff base. The structures of synthesized compound have been identified on the principles of their mass, 1H - NMR, Ft - IR, Mass spectrum and C, H, N elemental analysis. The synthesized compounds which founded…mehr

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Produktbeschreibung
The five member ring as 1,3,4 - thiadiazole and 1,3,4 - Oxadiazole bearing Schiff bases derivatives were prepared in our study by reacting the 1,3,4 - thiadiazole part with 1,3,4 - oxadiazole part in ethanol to produce 1,3,4 - oxadiazole hydrazinyl - 1,3,4 - thiadiazole, which were treated with aromatic aldehyde to produce of 1,3,4 - thiadiazole hydrazinyl 1,3,4 - oxadiazole bearing Schiff base. The structures of synthesized compound have been identified on the principles of their mass, 1H - NMR, Ft - IR, Mass spectrum and C, H, N elemental analysis. The synthesized compounds which founded have a strong antimicrobial activity, were assessed to their antibacterial activity by inhibition the growth of 3 strains of Gram negative bacteria Pseudomonas auerogenosia, Escherichia coli and one strain which produce enzyme called extended spectrum Beta lactemse (ESBLs) and 2 strains of Gram positive bacteria such as Bacillus cereus and Staphylococcus aureus.
Autorenporträt
Lecturer Bassam Abdul Hussein Alsafee M.Sc Organic Chemistry, Lecturer Maitham Mohamed Abdulridha M.Sc In Organic Chemistry, Lecturer Ali Taher Abbas M.Sc Micro Biology.