Chronic Periodontitis is considered to be an inflammatory disease and is characterized by the damaging the connective tissue and supporting bone due to secondary infection by periodontal bacteria. Substantial evidence has implicated Porphyromonas gingivalis (P.g) and Aggregatibacter actinomycetemcomitans (A. a) to be the pathogenesis of the chronic periodontitis. Ozone is a powerful antimicrobial agent which possess an effect against bacteria, fungi, protozoa, and viruses by damaging its cytoplasmic membrane.
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