Predstavleny svedeniya ob osnovnykh klassakh antibakterial'nykh preparatov, rassmotreny klassifikatsii i osobennosti primeneniya; dana kratkaya kharakteristika protivogribkovym preparatam i pokazaniyam k ikh naznacheniyu v khirurgii. Izlozheny voprosy antibiotikoprofilaktiki posleoperatsionnykh gnoynykh oslozhneniy i antibiotikoterapii khirurgicheskikh infektsiy, takikh kak ranevye infektsii, intraabdominal'nye infektsii, vklyuchaya kholangit, infitsirovannyy pankreatit i peritonit, a takzhe obobshcheny rekomendatsii po antibiotikoterapii sepsisa, kateter-assotsiirovannykh infektsiy, osteomielita, artrita i infitsirovannoy diabeticheskoy stopy. Osoboe vnimanie udeleno allergicheskim reaktsiyam na antibiotiki i probleme antibiotikorezistentnosti vozbuditeley khirurgicheskikh infektsiy. Dlya internov, klinicheskikh ordinatorov, khirurgov i vrachey drugikh spetsial'nostey.