The present Book "Antimicrobial Activity of Portuleca oleracea L" is the outcome of Authors practical Research work, Portuleca oleracea L is an Important medicinal plant that has been used in traditional medicine. The aim of present study to investigate antimicrobial properties of Chloroform & Ethanol extracts Arial parts of Portuleca oleracea L against 5 Bacteria and 3 Fungi by Agar diffused Method. The books contain the basic research Methodology of Pharmacology useful of researchers. The matter has been lucidly, presented ,orderly, arranged & Profusely illustrated .References have been added at the end in order to guide the Researcher to the Classical & Current literature.