Antimicrobial and Phytochemical Studies on Extracts of Bucholzia coriacea Seeds - Adimabua, Kingsley; Awemu, G. A.; Aniekan, A. U. D.; Odiegwu, A. M.
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Research Paper (postgraduate) from the year 2013 in the subject Chemistry - Bio-chemistry, grade: none, Madonna University Elele, Nigeria, course: Pharmaceutical and Medicinal Chemistry, language: English, abstract: The in vitro antimicrobial activity of crude methanol and aqueous extracts of the seeds of Bucholzia coriacea were investigated. The extracts exhibited antimicrobial activities against Escherichia coli, klebsiella pneumonia, Bacillus subtilis, Staphylococcus aureus, Salmonella typhii, Bacillus cereus and Pseudomonas aeruginosa. The minimum inhibitory concentration (MIC) of the…mehr

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Produktbeschreibung
Research Paper (postgraduate) from the year 2013 in the subject Chemistry - Bio-chemistry, grade: none, Madonna University Elele, Nigeria, course: Pharmaceutical and Medicinal Chemistry, language: English, abstract: The in vitro antimicrobial activity of crude methanol and aqueous extracts of the seeds of Bucholzia coriacea were investigated. The extracts exhibited antimicrobial activities against Escherichia coli, klebsiella pneumonia, Bacillus subtilis, Staphylococcus aureus, Salmonella typhii, Bacillus cereus and Pseudomonas aeruginosa. The minimum inhibitory concentration (MIC) of the ethanol extract was between 0.50 ¿ 6.00 mgml-1 while the minimum bactericidal concentration ranged from 2.0 ¿ 10.0. The methanol and water extracts exhibited antifungal activity against Candida albicans and Aspergillus niger with zones of inhibition of 7.50 and 2.80mm for Candida albicans; and 6.0 and 2.0 for Aspergillus niger. Phytochemical screening revealed the presence of tannins, saponins, terpenoids, cardiac glycosides and alkaloids in the ethanolic and water extracts. The ability of the ethanol extract of Bucholzia coriacea seeds to inhibit the growth of bacteria and fungi is an indication of its broad spectrum antimicrobial potential which justifies its utilization in traditional medicine in treatment of infections.
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Autorenporträt
Biography of Kingsley Adimabua: Kingsley Adimabua is a dedicated and experienced Humanitarian and Development worker hailing from Abuja, Nigeria. With a career spanning 11 years, Kingsley has made significant contributions to various esteemed organizations within the field. His passion for making a positive impact on communities and his expertise in Monitoring and Evaluation (M&E) and Information and Knowledge Management have set him apart as a strong candidate. Throughout his professional journey, Kingsley has had the privilege of working with reputable organizations such as Malaria Consortium, Christian Aid, Cuso International, Save the Children, Oxfam Novib, eHealth Africa, CBM International, and Palladium in Nigeria. His notable achievements include establishing a harmonized Post Distribution Monitoring system for a consortium of organizations involved in the Nigerian Joint Humanitarian Response and implementing effective Information and Knowledge management systems for Oxfam