Table of contents:
Introduction. Chemotherapy of microbial infections. The antimetabolites: folate metabolism as a target for antimicrobial drugs. The cell wall as a target for antimicrobial drugs. Synthesis of nucleic acids as a target for antimicrobial drugs. Protein synthesis as a target for antibiotics. Membrane-active drugs effective against bacteria and fungi. Chemotherapy of protozoal infections.
Antimicrobial drugs are of central importance in combating illnesses such as typhoid, malaria, meningitis and influenza. This book describes the mode of action for the major classes of drugs. Where appropriate, the side-effects of the drugs are described together with the mechanisms by which resistance to them may arise. Among the major questions addressed are: How do the major classes of antimicrobial drugs work? What are the significant side-effects? How does resistance to these drugs arise? What strategies are there for overcoming resistance? Are we running out of effective drugs?
Antimicrobial drugs are of central importance in combating illnesses such as typhoid, malaria, meningitis and influenza. This book describes the mode of action for the major classes of drugs. Where appropriate, the side-effects of the drugs are
Introduction. Chemotherapy of microbial infections. The antimetabolites: folate metabolism as a target for antimicrobial drugs. The cell wall as a target for antimicrobial drugs. Synthesis of nucleic acids as a target for antimicrobial drugs. Protein synthesis as a target for antibiotics. Membrane-active drugs effective against bacteria and fungi. Chemotherapy of protozoal infections.
Antimicrobial drugs are of central importance in combating illnesses such as typhoid, malaria, meningitis and influenza. This book describes the mode of action for the major classes of drugs. Where appropriate, the side-effects of the drugs are described together with the mechanisms by which resistance to them may arise. Among the major questions addressed are: How do the major classes of antimicrobial drugs work? What are the significant side-effects? How does resistance to these drugs arise? What strategies are there for overcoming resistance? Are we running out of effective drugs?
Antimicrobial drugs are of central importance in combating illnesses such as typhoid, malaria, meningitis and influenza. This book describes the mode of action for the major classes of drugs. Where appropriate, the side-effects of the drugs are