Antimicrobial Resistance
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Antimicrobial resistance has existed in nature long before the discovery of antibiotics. The mechanisms of resistance are prevalent among the bacterial population. Over a period of time and facilitated by indiscriminate usage of antibiotics, these mechanisms are transferred from one type of bacteria to another, including the pathogenic ones. In addition, the rate of discovery of novel antimicrobials is much slower than the rate of evolution of antimicrobial resistance. Therefore, there is a need for alternative strategies to control antimicrobial resistance to save lives. In this book, the…mehr

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Produktbeschreibung
Antimicrobial resistance has existed in nature long before the discovery of antibiotics. The mechanisms of resistance are prevalent among the bacterial population. Over a period of time and facilitated by indiscriminate usage of antibiotics, these mechanisms are transferred from one type of bacteria to another, including the pathogenic ones. In addition, the rate of discovery of novel antimicrobials is much slower than the rate of evolution of antimicrobial resistance. Therefore, there is a need for alternative strategies to control antimicrobial resistance to save lives. In this book, the novel strategies to combat antimicrobial resistance are described, emphasizing collaborative measures of control. We describe the concerted efforts undertaken by global communities to combat antimicrobial resistance in detail. The most efficient strategy could be a behavioral change towards indiscriminate consumption, usage, and prescription of antibiotics.
Autorenporträt
Dr. Sunil D. Saroj (Associate Professor, Symbiosis School of Biological Sciences, Symbiosis International (Deemed University), India) During my Ph.D. in Microbiology from the Bhabha Atomic Research Centre, India, I was exposed to the fascinating life of microbes. Bacterial pathogens have efficient mechanisms to overcome the stress that could affect their growth and survival. The stress factors include both growth-promoting and growth-inhibiting molecules. The biggest challenge the bacterial pathogens must face is from antimicrobials, bacteriophages, and the host immune system. In nature, these bacterial pathogens are present in close association with other bacteria and their hosts. To overcome these challenges and preserve their existence, the bacteria have developed communication systems, wherein they share chemical and genetic information with the other bacteria. The role of these interspecies communications in virulence and antimicrobial resistance was pursued further during my post-doctoral experience at the Chiba University (Japan), Emory University (USA), and Stockholm University (Sweden). I understand that the issue of antimicrobial resistance could not be resolved by just discovery of novel antibiotics; additional novel intervention strategies are required.