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Medicinal plants are an important therapeutic aid for various ailments. Scientific experiments on the antimicrobial properties of plant components were first documented in the late 19th century. In India, from ancient times, different parts of medicinal plants have been used to cure specific ailments. Today, there is wide spread interest in drugs derived from plants. This interest primarily stems from the belief that green medicine is safe and dependable, compared to the costly synthetic drugs that have adverse effects. To determine the potential and promote the use of herbal medicine, it is essential to intensify the study of medicinal plants that find place in folklore. Pathogenic organisms are life forms that cause human diseases. They can harm human health in several ways. All microbes show resistance to antibiotics. Also, Indian Medicinal plants contain many antimicrobial agents and properties. Hence, an attempt has been made to find out newer components from the Indian Medicinal plants, which have antimicrobial properties and also cheaper and non toxic to the environment.