Free radical production in the body increases during exercise.This is accompanied by a concomitant increase in the endogenous antioxidant system.However,when this antioxidant system is overwhelmed by increased generation of free radicals,oxidative stress will occur. Oxidative stress that leads to lipid peroxidation and damage to cellular proteins and DNA has been implicated in muscular fatigue.One of the strategies to ameliorate exercise-induced oxidative stress is by ensuring that the antioxidant system in our body is functioning optimally.Hence,antioxidant supplements have often been recommended.Vitamin E is one of the nutrients that have shown promise as a protective antioxidant defenses against free radicals.This book provides current information on the sources of free radicals during exercise,particularly in the heat,antioxidant defenses against free radicals and effects of vitamin E supplementation on oxidative stress during exercise and exercise-induced muscle damage.The information contained in this book will be beneficial to professionals and individuals who are involved in the area of sports nutrition,antioxidants and exercise.