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In all processes of vertebrate postembryonic development, amphibian metamorphosis displays the most prominent transformation, which includes the typical programmed cell death in regressing or remodeling organs. Attention in the present study was thus directed to erythrocyte replacement, hepatic organization and hormonal regulation during metamorphosis of four tested species of anura (Bufo regularis, Bufo viridis, Rana bedriagae and Ptychadena mascareniesis).