Food safety management system is a systematic method that serves as the foundation for assuring food safety in the modern world. This system was designed to be used to prevent the occurrence of food borne hazards from the first point of production chain through manufacturing, storage to the end user and his satisfaction. The purpose of the present work was to pay increase attention to wheat grain and wheat flour quality by implementation of food safety management system by applying ISO 22000 and HACCP as a safety tools in wheat milling industry, from receiving wheat grains to produce their product (flour streams).